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CHAPTER 39- Gentamycirn antibiotic name Drug Class & Indication(s Contraindications Levofloxacin Ciprofloxacin Fluoroquinolone antibiotic Tobramycin Aminoglycoside antibiotic Nephrotoxicity & Ototoxicity!! Common Adverse Effects EKG changes: tendonitis/tendon rupture; neuro changes, such as confusion & seizures; risk for altered mental status(elderly) ajor Interactions ex. CYP450 Nurse Considerations: (Examples: Age, renal/hepatic precautions, safety with administration lab monitoring teaching)

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Answer: Contraindications for aminoglycoside antibiotics : Hypersensitivity to aminoglycoside or bisulfites.

Drug interactions: When coadministrated by patient with renal insufficiency, inactivated by penicillin and cephalosporin. Increased chances of ototoxicity with loop diuretics.

Nursing consideration: Nurse should do the assessment since the therapy starts. Monitoring and examine the auto hearing process as it may cause loss of hearing. And also monitor the neurologic conditions.

*Fluoroquinolones antibiotics:

Contraindications: Fluoroquinolones are contraindicated people of athelete group. This is also contraindicated in children, pregnancy, and breastfeeding women as it may affect the development of cartilage.

Drug interactions: This group of drug interacted with  warfarin, and nonsteroidal anti-inflammatory drugs.

Nursing consideration: Monitoring the hearing functions, encouraging fluid intake and small meals.

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