why the dopamine receptor is considered adrenergic when the definition of an adrenergic receptor is a...
why the dopamine receptor is considered adrenergic when the definition of an adrenergic receptor is a response to epinephrine and norepinephrine?
Homework Answers
The dopamine receptor is considered adrenergic because it is linked to G proteins like the epinephrine and norepinephrine, thus having similar signal transduction cascades.
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why the dopamine receptor is considered adrenergic when the
definition of an adrenergic receptor is a...
Epinephrine is a ligand for the beta-adrenergic receptor. When activated the beta-adrenergic receptor undergoes a conformational...
Epinephrine is a ligand for the beta-adrenergic receptor. When activated the beta-adrenergic receptor undergoes a conformational change that results in the activation of the G protein GsLaTeX: \alpha α . Which of the following secondary messengers would you expect to be increased when epinephrine binds to a beta-adrenergic receptor? DAG cGMP cAMP Ca2+ phospholipase C IP3
Question 1 (1 point) Vasoconstriction occurs when epinephrine (adrenaline) binds to the a-adrenergic receptor on vascular...
Question 1 (1 point) Vasoconstriction occurs when epinephrine (adrenaline) binds to the a-adrenergic receptor on vascular smooth muscle cells. One way to treat high blood pressure is to administer competitive inhibitors that bind to this receptor. The Kd for binding of epinephrine to this receptor is ~UM. Based on the measured affinity (Kd) of the following drugs for the a-adrenergic receptor, which might be good candidates for high blood pressure medication? Drug A: Kd = 0.6 M; Drug B: Kd...
Epinephrine B-Adrenergic receptor Adenylate cyclase GDP ATP Cyclic AMP ✓ Protein kinase A Protein kinase A...
Epinephrine B-Adrenergic receptor Adenylate cyclase GDP ATP Cyclic AMP ✓ Protein kinase A Protein kinase A Describe the steps by which epinephrine causes cAMP production. [Choose ] Epinephrine binds to the extracellular portion of the beta-adrenergic receptor [Choose] The binding of epinephrine causes dimerization of its receptor. Choose] On the intracellular side, this change propagates to membrane-bound heterotrimeric G proteins. This causes them to hydrolyze GTP. [Choose ] < [Choose ] The G-proteins then dissociate into their alpha and beta/gamma...
Recall the sites (effectors) of alpha1-, beta1-, and beta2-adrenergic receptors and state the expected responses from...
Recall the sites (effectors) of alpha1-, beta1-, and beta2-adrenergic receptors and state the expected responses from their activation by a suitable agonist. Classify the following agonists in terms of the adrenergic receptors they activate and the responses they cause as a result of direct receptor activation: (1) epinephrine, (2) norepinephrine, (3) phenylephrine, (4) isoproterenol, (5) terbutaline, and (6) dobutamine. Explain the difference between direct cardiac (beta1) effects of adrenergic agonists and reflex (baroreceptor reflex–mediated) effects of those same drugs, using...
Suppose that each β–adrenergicβ–adrenergic receptor bound to epinephrine converts 100100 molecules of the GαGα subunit to...
Suppose that each β–adrenergicβ–adrenergic receptor bound to epinephrine converts 100100 molecules of the GαGα subunit to the GTP-bound form, Gαs.Gαs. If each molecule of activated adenylate cyclase produces 1000 molecules of cAMP per second, how many molecules of cAMP are produced in 10 seconds10 seconds after the formation of a single complex between epinephrine and the β–adrenergicβ–adrenergic receptor? Assume the pathway is fully responsive. Molecules of cAMP = ??
What is the correct answer to the question below and why. Also, why is my answer...
What is the correct answer to the question below and why. Also,
why is my answer (marked with a dash through it) wrong.
x6. Smooth muscle of arterioles is populated with alpha-1 subtype adrenergic receptors ivation of alpha-1 receptors leads to vasoconstriction. Both epinephrine and norepinephrine can activate alpha-1 receptors, however norepinephrine has considerably higher affinity for the receptor, compared to epinephrine. If we used to the figure to the right to explain this, we would say that 100 A....
Epinephrine opposes insulin action. It works through the β2 adrenergic receptor to elicit the cAMP signaling...
Epinephrine opposes insulin action. It works through the
β2 adrenergic receptor to elicit the cAMP signaling
cascade (Tymoczko3e Fig 13.4; Berg8e Fig. 14.1). The image below is
of the hormone-bound, activated form of
the β2 adrenergic receptor. The red and blue
lines demarcate the boundaries of the outer and inner leaflets of
the lipid bilayer, respectively. Recall that one complete turn of
an α-helix contains 3.4 residues and is 5.4 Angstroms in length.
Using the alpha helix as a ruler and...
Drugs Affecting the Autonomic Nervous System_crossword puzzle Across 2. Drugs with a specific receptor affinity that...
Drugs Affecting the Autonomic Nervous System_crossword
puzzle
Across
2. Drugs with a specific receptor affinity that
mimic the body's natural chemicals.
4. Synthetic antimuscarinic drug used for the
treatment of overactive bladder.
6. The nurse should carefully monitor for this
potential side effect when giving a beta blocker.
8. Direct-acting cholinergic agonist used to
treat urinary retention.
9. Symptoms may include circulatory collapse,
hypotension, bloody diarrhea, shock, and cardiac arrest.
11. Receptor sites for the catecholamines
norepinephrine and epinephrine.
12....
Recall the sites (effectors) of alpha1-, beta1-, and beta2-adrenergic receptors and state the expected responses from...
Recall the sites (effectors) of alpha1-, beta1-, and beta2-adrenergic receptors and state the expected responses from their activation by a suitable agonist. Explain the difference between direct cardiac (beta1) effects of adrenergic agonists and reflex (baroreceptor reflex–mediated) effects of those same drugs, using norepinephrine, phenylephrine, and isoproterenol as examples. Identify the desired effects when a therapeutic dose of epinephrine is given for anaphylaxis and explain the actions of the drug that earn it the label “drug of choice” for anaphylaxis....
Are biogenic amine neurotransmitters such as dopamine considered to be proteins? No, it simply means that...
Are biogenic amine neurotransmitters such as dopamine considered to be proteins? No, it simply means that dopamine has at least one amine functional group in its molecular structure. No, dopamine cannot be a protein since proteins do not exhibit neurotransmitter activity. Yes, dopamine is a protein because of its expression of a nitrogen-containing amine group. Yes, amines are naturally occurring organic compounds composed of amino acids. Prozac belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs),...
Question 1 (1 point) Vasoconstriction occurs when epinephrine (adrenaline) binds to the a-adrenergic receptor on vascular smooth muscle cells. One way to treat high blood pressure is to administer competitive inhibitors that bind to this receptor. The Kd for binding of epinephrine to this receptor is ~UM. Based on the measured affinity (Kd) of the following drugs for the a-adrenergic receptor, which might be good candidates for high blood pressure medication? Drug A: Kd = 0.6 M; Drug B: Kd...
Epinephrine B-Adrenergic receptor Adenylate cyclase GDP ATP Cyclic AMP ✓ Protein kinase A Protein kinase A Describe the steps by which epinephrine causes cAMP production. [Choose ] Epinephrine binds to the extracellular portion of the beta-adrenergic receptor [Choose] The binding of epinephrine causes dimerization of its receptor. Choose] On the intracellular side, this change propagates to membrane-bound heterotrimeric G proteins. This causes them to hydrolyze GTP. [Choose ] < [Choose ] The G-proteins then dissociate into their alpha and beta/gamma...
What is the correct answer to the question below and why. Also,
why is my answer (marked with a dash through it) wrong.
x6. Smooth muscle of arterioles is populated with alpha-1 subtype adrenergic receptors ivation of alpha-1 receptors leads to vasoconstriction. Both epinephrine and norepinephrine can activate alpha-1 receptors, however norepinephrine has considerably higher affinity for the receptor, compared to epinephrine. If we used to the figure to the right to explain this, we would say that 100 A....
Epinephrine opposes insulin action. It works through the
β2 adrenergic receptor to elicit the cAMP signaling
cascade (Tymoczko3e Fig 13.4; Berg8e Fig. 14.1). The image below is
of the hormone-bound, activated form of
the β2 adrenergic receptor. The red and blue
lines demarcate the boundaries of the outer and inner leaflets of
the lipid bilayer, respectively. Recall that one complete turn of
an α-helix contains 3.4 residues and is 5.4 Angstroms in length.
Using the alpha helix as a ruler and...
Drugs Affecting the Autonomic Nervous System_crossword
puzzle
Across
2. Drugs with a specific receptor affinity that
mimic the body's natural chemicals.
4. Synthetic antimuscarinic drug used for the
treatment of overactive bladder.
6. The nurse should carefully monitor for this
potential side effect when giving a beta blocker.
8. Direct-acting cholinergic agonist used to
treat urinary retention.
9. Symptoms may include circulatory collapse,
hypotension, bloody diarrhea, shock, and cardiac arrest.
11. Receptor sites for the catecholamines
norepinephrine and epinephrine.
12....
Are biogenic amine neurotransmitters such as dopamine considered to be proteins? No, it simply means that dopamine has at least one amine functional group in its molecular structure. No, dopamine cannot be a protein since proteins do not exhibit neurotransmitter activity. Yes, dopamine is a protein because of its expression of a nitrogen-containing amine group. Yes, amines are naturally occurring organic compounds composed of amino acids. Prozac belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs),...
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