Question

. True or False: A trait transmitted as an autosomal recessive is expressed only in the homozygous individual 2. Fill in the blank: If both alleles of a pair are fully expressed in the heterozygous state, the genes are said to be 3. Name the four major forms of treatment directed against malignant tumors: 2. 3. 4. Fill in the blank: Cancer is second only to heart disease as a cause of death in the United States, accounting for almost % of all deaths in this country. 5. Fill in the blank: Thrombocytopenia is a decrease in 6. Fill in the blank: The term refers to a neoplasm of hematopoietic tissue. 7. Name the three large groups of genes which play important roles in regulating cell functions, and derangements of these genes are associated with the formation of tumors: 2. 8. Name the three groups of malignant tumors: 2. 3. 9. True or False: Chorionic villus sampling can be performed at 5-7 weeks gestation. 10. True or False: Hemophilia is transmitted on the X 1. Fill in the blank: Down syndrome is the most common chromosomal abnormality, having an incidence of about in births.

Answer 1

1. True. An autosomal recessive trait requires both the alleles to express its effects or two copies of an abnormal gene must be present in order for the disease or trait to develop.

2. Codominant.

3. Treatment of Malignant tumors:

• Surgery
• Radiation Therapy
• Chamotherapy
• Targeted Therapy (immunotherapy) and Hormonal Therapy

4. 21.7 %. Heart diseases cause 23.1 % deaths in united states.

5. Platelets.

6. Leukemia.

7. Group of genes responsible for cancer:

• Proto-Oncogenes
• Tumor suppressor genes
• DNA repair genes

8. Three groups of malignant tumors:

• Carcinoma
• Sarcoma
• Leukemia and Lymphoma

9. False. CVS is performed between 10th to 14th weeks of pregnancy.

10. True. Hemophilia is transmitted as X - linked recessive trait.

11. 1 in 1000 to 1100 live births worldwide.