Question

QUESTION7 A dient who takes Theo-24 (theophyline) for asthma, is experiencing theophyline toxicity Which of these may be a contributing factor? (Select all that apply) First pass effect Forgetfulness (double dosing) O Chewing the capsule Cirrhosis with Gallstones O Taking the medication with food
please help

Answer 1

Answer -

First pass metabolism

Forgetfulness(double dosing)

Chewing the capsule

Cirrhosis of liver with gall stone

They all affect the theophylline toxicity.

First pass metabolism directly enhance the plasma concentration of drug without some breakdown into liver.

Double dose have main cause of toxicity

Chewing the capsule increases the effect by first pass metabolism and cirrhosis by unable to detoxification

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