Question

1) James is addicted to playing video games. Every time he passes by the television, he feels an overwhelming urge to switch it on and play on his gaming console. He often gives in to these urges and feels immense pleasure while playing video games. Which part of James's brain is stimulated in such situations?

• The parietal lobe of the cerebral cortex

• The cerebellum

• The medulla oblongata

• The limbic system

2) Select the contributing factor that leads to physical dependency while taking barbiturates.

• Greater therapeutic dosages taken on a regular basis for less than 2 weeks

• Greater therapeutic dosages taken on a regular basis for more than 2 years

• Greater therapeutic dosages taken on a regular basis for more than 1 to 2 months

• None of the above

3) Use your critical-thinking skills to determine a pharmacokinetic effect of barbiturates as a result of enzyme induction.

• Enzyme induction leads to slower metabolism of the barbiturate in the liver and increased duration of action.

• Enzyme induction leads to faster metabolism of the barbiturate in the liver and decreased duration of action.

• Enzyme induction leads to slower metabolism of the barbiturate in the liver and decreased duration of action.

• None of these are correct.

Answer 1

1.ANSWER: D.THE LIMBIC SYSTEM

REASON: Due to increased released of dopamine immense pleasure feeling to one particular thing happens.

2.ANSWER: C. Greater therapeutic doses taken on a regular basis for more than 1 to 2 months.

REASON: Because it is a CNS modulator drug, it can cause dependence earlier.

3.ANSWER:C. Enzyme induction leads to faster metabolism of barbiturates in the liver and decreased duration of action.

REASON: Due to chronic use of barbiturates, it induces the microsomal enzymes increasing the metabolism of drugs by these enzymes.