Question

Suppose that you have been hired by the Florida state student health services department to design a case-control study to assess the following hypothesis among Florida state students at Florida State :Irregular sleep patterns increase the risk of headaches.

Be sure that your design addresses the following elements:

1. Refine the study hypothesis so that it is as specific as possible and contains all elements of a “good” hypothesis.
2. How will you identify and define the cases?
   • Are there any exclusion criteria that you would apply?
3. How will you sample from the underlying population for your “controls”?
   • Who will you select as controls?
   • How will you select them?

4. How will you define the exposure of interest?
   • How will you collect the information on exposure?
5. What other information do you want to know about participants that may be related to the exposure of interest and/or the outcome (potential confounders)? Of these, what will you be able to collect and what will you be unable to collect?
6. Which measures of disease frequency and association will you calculate?
7. What are the strengths and limitations of your study?
   • Which limitations could be removed by using a different study design?
8. What other information would you like to know to design this study?

Answer 1

According to the above given question by the folloding Solution as Given that Irregular cleep pallerne increase the risk of headaches among fbrida state stedents. We need to follow closign address of the given elements. define the study hypothesis it is specific as possible and contains all elements of the good hypothesis . Hypothesis : Irregular sleep patterns increase the risk of headaches among Florida state students. - Identify the cases will be students enrolled in Florida stale Oniversity and hailing soregular sleep patterns Exclusion criteria includes previous history of migraine ; truma (8) head injury. - Stedents will selective Connells 5 the underlying poporulation will be selected from the same stedents but not having arregular sleep pallerns : Cams Te is Sample from the underlying populalion Scanned with

They can be classmates (n) friends of Cases. > Exposiere of Inlēresto * Exposure of Interest in the irregular sleeping patterns * information about this exposure can be - Obtained by interniewing the cases and Controlls o an that form we can collect the information. o the Exposure of interest / the outcome :- * We known about potential confounders incle de mental stress , cle preapon, anitely, gender Socioeconomic factors. Ele & which could also contribute to headache these can be some what ekminated through matching Cases with controlls. * Odder Rako between exposure and outcome 1. Can be Calculated Strenght of - Limitations of our stody i- - komitations of our steedy is strengths include establishing association Between the efect I cause and CS study design which can conducted easily of cheep

* Causation can not be Limitation include established Stredy design & & Causation can be established by closing Cohort steedy (08) randomised control trails. & the study design of any evidence of association Retween irregular sleep pattern and headache from previous studies will help us to design the stredy better and also to eliminate possible confounding factors. Scanned with CamScanner