Question

A randomized controlled trial examined the efficacy of adding a 4-week intensive and brief psychodynamic psychotherapy (IBPP) to treatment-as-usual (TAU) for inpatients with DSM-IV major depressive episode. Depression severity was evaluated by the Montgomery-Asberg Depression Rating Scale (MADRS) at baseline and post-treatment (week4). Treatment response was defined a priori as a reduction in symptom severity of 46% or higher of the baseline score. Chi-Squared test result for the effect of IBPP on treatment response is shown in the table below (level of significance alpha=.05). Please select ALL correct interpretations of the Chi-squared test result.

	Responsers n (%)	Non-responsers n (%)	Chi-Square	OR	95% CI	p
IBPP	23 (41.1%)	33 (58.9%)	4.92	2.44	(1.10 – 5.42)	0.027
TAU	14 (22.2%)	49 (77.8%)

	Responsers n (%)	Non-responsers n (%)	Chi-Square	OR	95% CI	p
IBPP	23 (41.1%)	33 (58.9%)	4.92	2.44	(1.10 – 5.42)	0.027
TAU	14 (22.2%)	49 (77.8%)

1. At week 4, patients receiving IBPP are 2.77 times as likely as those receiving TAU to reduce symptom severity of 46% or more.
2. At week 4, the treatment response rate for the IBPP group does not significantly differ from that for the TAU group.
3. At week 4, the treatment response rate for the IBPP group is significantly higher than that for the TAU group
4. At week 4, patients receiving IBPP are 1,77 times higher than those receiving TAU to reduce symptom severity of 46% or more.
5. E. the 95% CI ( Confidence Interval) of 1.17-6.59 for the Odds Ration (OR) indicates the test result is not significant.

Answer 1

D. At week 4, patients receiving IBPP are 1,77 times higher than those receiving TAU to reduce symptom severity of 46% or more.

in this sample data the the responders in the intervention group is 23 campared to 14 in the TAU group that will be approximately 1.77 times