Margery's maternal grandparents moved to Cincinnati, Ohio, from Ireland before her mother was born. Both her paternal grandparents were of Scottish ancestry. Margery recently married Sam, and they want to put off having children until they are financially stable. She is interested in advice about birth control and asks for information about oral contraceptives during her routine physical examination. You take a family history and find out that Margery's mother has a history of blood clots, and her paternal grandfather died from a stroke. 1. Why is the history of blood clots and stroke important to consider in Margery's decision regarding oral contraceptives? 2. How is Margery's Celtic background relevant to her risk of blood clots? 3. Should you suggest that she have genetic testing for factor V Leiden? 4. How could your concerns be handled in a professional manner consistent with your scope of practice?
1.Oral contracceptibe medications usually releases progesterone and estrogen .This is mainly because of the estrogen which can cause blood clots which can block the blood supply to brain and cause stroke.Though women have a very minimal chance of getting it.A history of it can predict the risk and side effect of the contraceptive pill when used in this patient
2.A family history of blood clot and stroke with use of contraceptive pills can strongly contribute to the increased risk of hereditary passage to Margery from mother (dominant trait) and paternal grandfather (recessive trait)
3.The factor V Leiden is a marker which used to identify the mutated gene in factor V.When there is a mutation in the factor V it can cause blood clots.Doing this test can enable to assess the press end of any carrier of the gene .
4.Some of the concerns which can be handled in a professional manner are
Margery's maternal grandparents moved to Cincinnati, Ohio, from Ireland before her mother was born. Both her...