Question

2. Ms. George is a 32-year-old computer programmer eorge is a 32 year-old computer programmer. Over the last several months, she has had th ased episodes of a burning sensation in the mid epigastrium and back. The pain subsides after eating. Based on her history, the physician orders an endoscopy that reveals several peptic ulcers. Treatment of the ulcers includes antibiotics, proton pump inhibitors, and bismuth salts. Learning Objectives 1 and 3) incre Correlate Ms. George's clinical presentation to the pathophysiology of peptic ulcers. Ms. George asks why eating decreases her pain; how does the nurse respond? Explain the rationale for the prescribed pharmacologic therapy. a. b. c.

Answer 1

a) Ms. George's clinical manifestations like increased episodes of burning sensation in the mid epigastrium and back, which is associated with excessive gastric acid secretion proved as the significant pathogenesis of peptic ulcers.

b) In this case eating subsides the peptic ulcer pain of Ms. George because food acts as buffer and hence food reduces the gastric acid generated pain as in fed state rather than in the empty stomach.

c) In the case of Ms. George prescribed pharmacotherapy is: antibiotics, proton pump inhibitors and bismuth salts.

Because proton pum inhibitors inhibit the release of gastric acid (HCl), because proton pump inhibitors inhibit the release of gastric acid (HCl), hence it’s beneficial, Antibiotics are used to reduce further ulcer associated infections and bismuth salts is used for cytoprotective as well as ulcer healing properties.