Question

9. The early stage of Mycobacterium tuberculosis infection is characterized by the formation of which of the following lesions in the lungs: a. granulomatous b. exudative c. tubercle d. eschar e. induration 10. Antibiotic therapy used in the treatment of M. tuberculosis has become more complicated by the development of multiple drug resistance. All of the following drugs, alone or in combination, a. chloramphenicol b. isoniazid c. rifampin d. ethambutol e. pyrazinamide have been shown effective in the treatment of the bacteria EXCEPT CASE STUDY #3 A YOUNG HEALTHY WOMAN EAGERLY EXPECTED THE BIRTH OF HER FIRST CHILD. PRENATAL CARE INSTRUCTIONS WERE FOLLOWED AND ALL INDICATIONS APPEARED NORMAL. UNFORTUNATELY, A STILL BORN FETUS WITH NEONATIAL MENINGITIS WAS THE OUTCOME. THE MOTHER WAS AN ASYMPTOMATIC CARRIER OF THE PATHOGEN. 11. Such an occurrence could result from the intrauterine or vaginal colonization by: a. Listeria monocytogenes b. Bacteroides fragilis c. Clostridium difficile d. Clostridium perfringens e. Gardnerella vaginalis 12. If a sample of the CSF from the infant were Gram stained, observed bacteria would a, Gram negative cocci b. Gram negative bacilli Gram variable bacilli d: Gram positive cocci Gram positive bacilli 13. The drug of choice in the treatment of this pathogen is: b. penicillin c. cephalosporin C d. streptomycin e. amphotericin B

Answer 1

9 c. The virulence factors can survive phagocytosis living inside macrophages and moving them to deep lung tissue and produce tubercles.

10 b,c.In MDR TB,the organism  is resistant to both isoniazid and rifampin,according to WHO.

11aEnteric gram negative rods and Listeria Monocytogenes reach the fetus transplacentally and cause infection.

12 e The organism is gram-positive, catalase -positive rod.

13 b Ampicillin belonging to the penicillin is the first line of drug for the treatment of infection.