Question

9.   Which of the following shows the insulins in the correct order from shortest to longest acting in duration of action?

A. Lente, Ultralente, regular, NPH   B. Regular crystalline, Ultralente, Lente, NPH   C. Regular crystalline, NPH, Lente, Glargine   D. Ultralente, Lente, NPH, regular

Answer 1

C.

Regular is a short-acting insulin.

Intermediate-acting insulins include

NPH and

lente.

insulin glargine are long-acting insulins.

Regular insulin  is used with a proper diet and exercise program to control high blood sugar in people with diabetes mellitus.This man-made insulin product is the same as human insulin.It replaces the insulin that human body would normally make. It is a short-acting insulin

neutral protamine Hagedorn

NPH insulin is an intermediate-acting insulin; NPH stands for neutral protamine hagedorn. NPH insulin starts to lower blood glucose within 1 to 2 hours after injection. It has its strongest effect 6 to 10 hours after injection, but keeps working about 10 hours after injection. It is also called N insulin.

Lente insulin is an intermediate-acting insulin. lente insulin starts to lower blood glucose levels within 1 to 2 hours after injection. It has its strongest effect 8 to 12 hours after injection but keeps working for 18 to 24 hours after injection.

Insulin Type	Onset	Peak	Duration
Short acting: regular insulin Usually taken about 30 minutes before a meal to cover blood glucose elevation from eating Used with longer-acting insulin	30 min	2.5-5 hr	4-24 hr
Intermediate acting: insulin NPH [3] Covers the blood glucose elevations when rapid-acting insulins stop working Often combined with rapid- or short-acting insulin and usually taken twice a day	1-2 hr	4-12 hr	14-24 hr
Long acting: insulin glargine [4], ultralente insulin, insulin detemir Often combined, when needed, with rapid- or short-acting insulin Lowers blood glucose levels when rapid-acting insulins stop working Taken once or twice a day	3-4 hr	No defined peak	≥24 hr