Question

The local hospital has a neurological clinic yhat treats many patients with Parkinson’s disease. Why might each of the following patients treated this week at the clinic be prescribed a drug other than Sinemet?

a. Patient A has been taking Sinemet for 2 weeks and complains of fainting when getting out of bed, a racing heart, and loss of appetite.

b. Patient B is a self-confessed “health nut” who takes multiple vitamin supplements every day, including all of the B vitamins.

c. Patient C is taking Marplan for depression.

Answer 1

1.Patient A is prescribed another drug to sinemet because the patient has side effects like fainting while getting out of bed,faster heart rate and loss of appetite.The two side effects of fainting can be taken care by instructing the patient to get up slowly .Sinemet ffects the autonomic nervous system in normal times to regulate the heart function but sometimes it can lead to more control in the autonomic nervous system thus causing tachycardia .so the drug should be stopped

2.Patient B taken many multivitamins and is a health nut.utivitamins as it is doesn't have any interactions with Sinemet but since he is health but chances are that he may be taking iron supplements which has a serious interactions with sinemet.it can reduce the absorption of Sinemet thus increasing the Parkinson's symptoms

3.Patient B is on Marplan is a isocarboxacid is a irreversible monoamine oxidase inhibitor of hydrazine class which is used to treat depression as antidepressants.Marplan has a serious interactions with Sinemet which causes poor absorption of Sinemet causing a increased Parkinson's symptoms.

These are all the reasons why the physician prescribed a alternate drug to sinemet to each of these patients.