Amoxicillin 20 mg/kg/day divided q 8hr. is ordered for an 11 year old child with an ear, nose and throat infection. The child weighs 36 kg. Your bottle of amoxicillin is labeled 200 mg / 5 mL. How many mL of amoxicillin will you give the child at each dose? .
ANSWER.
* Calculation of ml of drug required in each dose.
Formula
Volume(ml) = Desired dose/Dose in hand * Quantity.
Here
Ordered dose = 20 mg/kg/day.
Weight of the patient = 36 kg
Dose required for the patient = 20 * 36
= 720 mg.
So
Desired dose(D) = 720 mg/day.
Dose in hand (H) = 200 mg
Quantity (Q) = 5 ml
As per above formula
Volume(ml) of drug required = D/H * Q
= 720/200 * 5
= 3.6 * 5
= 18 ml per day
Volume(ml) of drug required per each dose = 18 ml divided q8hr or 3 times a day.
= 18 / 3
= 6 ml per dose.
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