Question

Date POLYMERS Prelaboratory Assignment 1. Which part of this experiment must be performed under a fume hood? 2. Amino acids are the monomeric units that make up proteins. The reaction which joins amino acids is similar to the reaction used in the preparation of nylon. Two amino acids are shown below. Show the molecule that would result by joining the two amino acids shown below. CH, 0

Answer 1

Answen. 2 Condensation Jeaction ㅓakes place by the e moval of a waden mole cule anl the pnodluct ill be Gilycylalanine Mechanism Glycyl Alanine The amino gnoup of snight handed amino acil oil atłack on the conbonyl gmoup of lef hamded amino acid (Gnlgcine) (ilanine) 2. CH3 -H2O CH3 A dipeptide Gly Alq

Now the vuestion is what is meant by left handed amd ight handed anni no acid ? why the amino g oup of only he amino acid acf qs nu cleophile ? It is convention to umite the qmino ocid u hose canboxylic gnoup is active, on the let hand side and the amino acid whose am)no noup is active, on the snight hand side In actuel paractice, both the runctional gmoups of both the mino qcids oe active but it on oun choice that what podc we ane ininestedl to fo71Yn . Suppose e an 1c ω5Me a chemical neactian fon the synthesis of alanylglycine insteciel af glycylalanine, we must hqve to wnite finst the out it depe nds alanine qnd then that of glycine In pneactical pumpose, fhe aino gnoup of the amins acid is finst deacivated (pmotected) by some sum he1x modifications so thed only caunbaxy lic gnoup ot this amins acid il be available rom the วาcoctian one