A pharmaceutical company ran a clinical trial to test if drug X cures disease Y. A statistician named Z who is taking BIO 211 was given a task to perform a null hypothesis test. The test was perfect, and the null hypothesis was rejected at the alpha = 0.05 significance level. However, unbeknownst to Z, the company ran 39 extra clinical trials and secretly hired Z’s classmates to evaluate data obtained from each independent trial with the same null hypothesis test at the same significance level.
How could presumably independent data and independent hypothesis testing change the conclusion of a single test? Can you think of a strategy to fix this issue?
A pharmaceutical company ran a clinical trial to test if drug X cures disease Y. A...
A pharmaceutical company ran a clinical trial to test if drug X cures disease Y. A statistician named Z who is taking BIO 211 was given a task to perform a null hypothesis test. The test was perfect, and the null hypothesis was rejected at the alpha = 0.05 significance level. However, unbeknownst to Z, the company ran 39 extra clinical trials and secretly hired Z’s classmates to evaluate data obtained from each independent trial with the same null hypothesis...
please answer questions Figure 1. Vertical li indicate the 2.5% tails of the alternate distribution. In other words, the red areas (area 0 and 8) sum to 5%, and areas 2, 3, 7 also sums to 5%. dicate the 2.5% tails of the null distribution, while B and D alternate distribution null distribution test statistic Consider a two-sided null hypothesis test with 0.05 as significance level. From the above probability density plot, identify the corresponding areas, or test statistic value...
A certain drug is used to treat asthma. In a clinical trial of the drug, 23 of 250 treated subjects experienced headaches (based on data from the manufacturer). The accompanying calculator display shows results from a test of the claim that less than 8% of treated subjects experienced headaches. Use the normal distribution as an approximation to the binomial distribution and assume a 0.01 significance level to complete parts (a) through (e) below. 1-PropZTest prop<0.08 z=0.699378606 p=0.7578422729 ^p=0.0920000000 n=250 a....
A certain drug is used to treat asthma. In a clinical trial of the drug, 27 of 292 treated subjects experienced headaches (based on data from the manufacturer). The accompanying calculator display shows results from a test of the claim that less than 8% of treated subjects experienced headaches. Use the normal distribution as an approximation to the binomial distribution and assume a 0.01 significance level to complete parts (a) through (e) below. 1-PropZTest prop<0.08 z=0.785183294 p=0.7838269455 p=0.0924657534 n=292 a....
A certain drug is used to treat asthma. In a clinical trial of the? drug, 26 of 255 treated subjects experienced headaches? (based on data from the? manufacturer). The accompanying calculator display shows results from a test of the claim that less than 99?% of treated subjects experienced headaches. Use the normal distribution as an approximation to the binomial distribution and assume a 0.01 significance level to complete parts? (a) through? (e) below. a. Is the test? two-tailed, left-tailed, or?...
A certain drug is used to treat asthma. In a clinical trial of the drug, 19 of 250 treated subjects experienced headaches (based on data from the manufacturer). The accompanying calculator display shows results from a test of the claim that less than 8% of treated subjects experienced headaches. Use the normal distribution as an approximation to the binomial distribution and assume a 0.01 significance level to complete parts (a) through (e) below. 1-PropZTest prop<0.08 z = -0.233126202 p=0.4078317046 p=0.0760000000...
During a clinical trial on seasonal allergy, a pharmaceutical company obtains the following data about the undesirable effects of the type of medication administered to patients. (a) What kind of chi-square test would be most appropriate to analyse these data – goodness of fit or homogeneity (independence)? Explain. (b) Using the appropriate chi-square tests with a 5% significance level, determine if the undesirable effects to patients is independent to the types of medication taken. i. Using the appropriate Minitab report....
Acertain drug is used to treat asthma. In a clinical trial of the drug, 29 of 260 treated subjects experienced headaches (based on data from the manufacturer). The accompanying calculator display shows results from a test of the claim that loss than 11% of treated subjects experienced headaches. Use the normal distribution as an approximation to the binomial distribution and assume a 0.05 significance levello complete parts (a) through () below. Properest prop<0.11 20.075203346 0.5315963737 a. Is the lost two-tailed,...
A certain drug is used to treat asthma. In a clinical trial of the drug, 21 of 261 treated subjects experienced headaches (based on data from the manufacturer The accompanying calculator display shows results from a test of the claim that less than 10% of treated subjects experienced headaches. Use the normal distribution as an approximation to the binomial distribution and assume a 0.05 significance level to complete parts (a) through (e) below 1-PropZTest prop co.1 p-0.1463370241 p 0.0804597701 n-261...
question #12 A certain drug is used to treat asthma. In a clinical trial of the drug, 27 of 257 treated subjects experienced headaches (based on data from the manufacturer). The accompanying calculator display shows results from a test of the claim that less than 11% of treated subjects experienced headaches. Use the normal distribution as an approximation to the binomial distribution and assume a 0.05 significance level to complete parts (a) through (e) below. 1-Prop Test prop<0.11 2- -0.253169571...