Draw compound 1 in a chair conformation that is suitable to explain the E2 elimination to...
Question 1 a) Draw the mechanism for the following E2 reaction. Use a chair conformation to illustrate the correct geometry between the leaving group and the hydrogen being eliminated. Tso NaOCHz + CH,OH + NaOTs b) Draw the 5-coordinate transition state that occurs during the Sn2 reaction below. NaCN DMSO c) Draw a complete mechanism for the transformation below. Be sure to include all curved arrows, intermediates, and by-products. H2SO4 (aq) OH OH الميم
10. Draw the product(s) of this E2 elimination reaction and draw the conformation of the substrate that leads to the product(s) and fulfils the stereoelectronic requirements for E2 elimination. Br (CH3),COK Pdt possible products conformation only product conformation possible products conformation possible products conformation only product
10. Draw the product(s) of this E2 elimination reaction and draw the conformation of the substrate that leads to the product(s) and fulfils the stereoelectronic requirements for E2 elimination. (CH3)3COK Pdt augu movie së zo mod core conformation possible products conformation only product I conformation possible products goy yo conformation possible products conformation only product
Complete the curved arrow electron-pushing mechanism of the following E2 elimination of 3-bromopentane and draw the structure of the organic product formed. Complete the curved arrow electron-pushing mechanism of the following E2 elimination of 3-bromopentane and draw the structure of the organic product formed.
Complete the curved arrow electron-pushing mechanism of the following E2 elimination of 3-bromopentane and draw the structure of the organic product formed. Use three curved arrows to show the conversion to the product. Draw the organic product of the E2 elimination of the 2-bromopentane.
Complete the curved arrow electron-pushing mechanism or the following E2 elimination of 3-bromopentane and draw the structure of the organic product formed. Use three curved arrows to show the conversion to the product. Draw the organic product of the E2 elimination of the 2-bromoperitane.
For the following reaction draw the chair conformation the produces the final product in the given E2 reaction. Draw a mechanism. Show the flow of electrons. Show oxygen-hydrogen bond formation, pi bond formation and carbon-leaving group breaking. Draw the product formed. Do not describe the reaction. Upload a picture. ,,OSO2CH3 NaOCH2CH3 HOCH2CH3
4. Predict the products of the following reactions & indicate whether they are most likely to go through an SN2, SN1, E1, or E2 mechanism. NaCN DMSO NaOH CH3OH heat Only one product is formed in the following E2 elimination reaction. Draw an arrow-pushing mechanism for the reaction and provide the correct product structure. Include a 3-D drawing (chair conformation) displaying proper stereochemistry of the transition state to explain formation of only the major product. CH3 •Br NaOCH3 ~"'CHS
Challenge CH 235R F 2019 Week 11 Problem #2 1. Predicting Major and Minor elimination products For each of the following alkenes, draw all possible elimination products for the following molecules, ignoring the mechanism. Indicate the major alkene product. noted II. E2 Eliminations on substituted cyclohexane halides Consider the two isomeric compounds below. a) Draw each in a chair conformation, b) Show the mechanism and final alkene product(s) that form from an E2 reaction with CH,O/CH,OH. c) If more than...
A chair conformation of compound A is shown: Answer both of the questions and explain A chair conformation of Compound A is shown: CH3 ring flip H3C CH3 Conformation A a) (apts) Draw a conformation of compound A as a result of ring flip. Circle the more stable conformation if possible. b) (5pts) Draw a Newman projection of conformation A.