Using an alcohol for one method and an alkyl halide for the other, show two ways...
2Beginning with an alcohol and an alkyl halide, draw two different routes to each of the following ethers using Williamson ether symthesis (Smith 9.6 Indicate the preferred route (if there is one), 8.
43. Tertiary alcohols with two identical alkyl groups attached
to the alcohol carbon can be made either from an ester and two
moles of a Grignard reagent, or from a ketone and one mole of a
Grignard reagent. Use retrosynthetic analysis to suggest one path
of each type to synthesize 1,1-diphenylethanol. (Click and drag the
appropriate image to the correct position in the following
reactions.)
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made...
(12 points) Esters can be prepared by nucleophilic substitution of an alkyl halide or via acyl substitution reactions. Show the compounds required to synthesize the ester two different ways. Be sure the product will be favored. 4. H0 alkyl halide nucleophile acyl derivative nucleophile Given the information in the question above, provide appropriate reactants above. hat does a nucleophilic substitution reaction look like in general? Acyl substitution?
(12 points) Esters can be prepared by nucleophilic substitution of an alkyl halide...
Tertiary alcohols with two identical alkyl groups attached to the
alcohol carbon can be made either from an ester and two moles of a
Grignard reagent, or from a ketone and one mole of a Grignard
reagent. Use retrosynthetic analysis to suggest one path of each
type to synthesize 2-phenyl-2-propanol. (Click and drag the
appropriate image to the correct position in the following
reactions.)
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either...
Tertiary alcohols with two identical alkyl groups attached to the
alcohol carbon can be made either from an ester and two moles of a
Grignard reagent, or from a ketone and one mole of a Grignard
reagent. Use retrosynthetic analysis to suggest one path of each
type to synthesize 3-methyl-3-pentanol. (Click and drag the
appropriate image to the correct position in the following
reactions.)
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either...
Tertiary alcohols with two identical alkyl groups attached to
the alcohol carbon can be made either from an ester and two moles
of a Grignard reagent, or from a ketone and one mole of a Grignard
reagent. Use retrosynthetic analysis to suggest one path of each
type to synthesize 2-methyl-2-butanol. (Click and drag the
appropriate image to the correct position in the following
reactions.)
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either...
14. Starting with an appropriate alkyl halide and using any
other needed reagents, outline the syntheses of each of the
following. When alternative possibilities exist for a synthesis,
you should choose the one that gives the better product. Indicate
whether each reaction follows an SN1 or SN2 reaction mechanism.
14. Starting with an appropriate alkyl halide and using any other needed reagents, outline the syntheses of each of the following. When alternative possibilities exist for a synthesis, you should choose...
3. Beginning with an alcohol and an alkyl halide, draw two different routes to each of the following ethers using a Williamson ether synthesis (Smith 9.6). Indicate the preferred route (if there is one). Predict the products of dehydration (elimination) of the following alcohol. Read Smith 9.8A. Predict which product will be the major product. H.SO 2-pentanol Write a mechanism for the dehydration reaction (steps showing the flow of electrons with curved arrows). Read Smith 9.8B & 9.9. 2-methylcyclopentanol
3.) Suggest two separate alcohol and alkyl halide combinations that could be used to produce the following ethers. Which combination would be the better choice, and why? (10 points)
3.) Suggest two separate alcohol and alkyl halide combinations that could be used to produce the following ethers. Which combination would be the better choice, and why? (10 points)
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 3-methyl-3-pentanol. (Click and drag the appropriate image to the correct position in the following reactions.)