Question

3. Give the products for each of the following reactions and clearly show any stereochemical features. CH3 NBS NaCN 4. "One of the most difficult problems in making synthetic proteins is maintaining stereochemistry when amino acids are connected together. The difficulty arises because amino acids tend to epimerize when "activated" for coupling. Epimerization can happen when the end of the amino acid chain forma the cyclic intermediate, as shown here. Explain why the ring structure can epimerize so readily." (9.30 from text) Cl 0 epimeriaztion 0

Answer 1