Question

flavin mononucleotide flavin adenine dinucleotide nicotinamide adenine dinucleotide coenzyme Q iron-sulfur clusters cytochromes Able to diffuse into mitochondrial matrix Unable to diffuse into mitochondrial matrix reset help Submit Hints My Answers Give Up Review Part

Answer 1

Ans. 1. Able to diffuse into mitochondrial matric:

                        A. NADH- Donates its electron to complex I. It can diffuse through mitochondrial matrix.             

2. Unable to diffuse into mitochondrial matrix

A. FMN - (cofactor integrated to complex I, non-dissociable)

B. FAD - (cofactor integrated to complex II, non-dissociable)

C. CoQ – Remains solvated in the mitochondrial inner membrane, and do not diffuse in matrix.

D. Fe-S center - (cofactor integrated to complex I and II, non-dissociable)

E. Cytochromes - (cofactor integrated to complex IV, non-dissociable). Also, cytochrome C remains associated with the mitochondrial inner membrane on the intermembrane space side. These can’t diffuse through mitochondrial matrix.    

2 4H 2H 2H' Cyt C CuA (Fe-S) UQ UQH Cyt a Cyt as FAD 4H 2H 2H FMN Succinate H20 2e +2H Fumerate NADH NAD+H ADP P ATP