Question

Evan T_ Problem Sets-201 7FAO Problem Set 10 2017pdf × Problem Set 10 Ch. 8.1-8.8 Fall 2017 Due: November 8 CHM 2510, section 02 5. (12 pts) For each pair, circle the reaction that will proceed faster via elimination. CH30 Br CH30H CH3O or C CH3OH CH3O CH3 or H3C CH3OH CH3OH Br OTs NaOH OTs NaOH or t-Bu DMSO t-Bu DMSO KOMe KOMe or diethyl ether diethyl ether 11:50 AM O Type here to search @^蕴恤4 E图 号1 17/2017 21

Answer 1

5. (12 pts) For each pair, circle the reaction that will proceed faster via elimination. снзо CH30 Br CH OH CI CH3OH C-Br bond is weaker compared to C-CI bond BPH3 or CH3OH CH3OH H and Br are trans position to each will undergo elimination faster OTs NaOH OTs NaOH or t-Bu DMSO t-Bu DMSO Attack of nucleophile from stereically less hindered side will be faster (tBu group is sterically hindered in reaction one KOMe KOMe 人 diethyl ether diethyl ether trans olefin formation is faster than cis olefin