Lysine has pKa values of 2.2 (alpha-COOH), 9.0 (alpha-NH3+), and 10.5 (R-group). Calculate the pI.
Lysine has pKa values of 2.2 (alpha-COOH), 9.0 (alpha-NH3+), and 10.5 (R-group). Calculate the pI.
3.40 |
5.60 |
6.35 |
9.75 |
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Lysine has pKa values of 2.2 (alpha-COOH), 9.0 (alpha-NH3+), and 10.5 (R-group). Calculate the pI. Lysine...
Part A Lysine has pka values of 2.2 (alpha-COOH), 9.0 (alpha-NH3*), and 10.5 (R-group). Calculate the pl. 3.40 5.60 6.35 9.75 Submit Request Answer wide Feedback MacB
Given the pKa values of Lysine (2.2, 9.0 and 10.5), what is the net charge of Lysine at: 1) pH = 4.2 (ANSWER SHOULD BE: 1) 2) pH = 13 (ANSWER SHOULD BE -1) Please show all calculations needed in order to get the answers in parentheses.
Calculate pI value of Asp (pka of COOH is 1.99 ,pka of NH3+ is 9.90 ,pKa of R group is 3.90)
1. Calculate pl value of His. COO H-C-CH NH3 Histidine (His, H) 2. The R group of lysine has an amino group that can be positively charged or lose a proton to become neutral. The pKa of the amino group is 10.8. Determine the fraction of amino group that is protonated at pH 9.8 and at pH 11.8.
1. Calculate pl value of His. COO H-C-CH NH3 Histidine (His, H) 2. The R group of lysine has an amino group...
Lysine has pKa values as illustrated on the diagram below a) H3N ОН рК, 2.18 NH3 pKa 10.53 + рка, 8.95 Calculate the isoelectric point for lysine i) Draw the predominant structure of lysine at pH>12 i b) The amino acid Tyrosine can be used in automated peptide synthesisers but this requires protected forms of the amino acid H2N ОН Он Tyrosine Show how you can synthesise N-protected and C-protected serine derivatives i) ii Show schematically a method to couple...
Please help: Free histidine in solution has three pKas (COOH=1.82; NH3+=9.17, and R-group=6.0). Determine if each group acts as a weak acid or base? And at pH7 does the protanted >,<,= deprotonated form of this side group ? example: weak ________ (acid/base) .... protanted _________ ( >,<,=) deprotonated. a: COOH = pkka = 1.82 b: NH3+ = = pka = 9.17 c: R group = pka = 6.0
Calculate PI for Argenine (pKa (carboxyl)= 3.1; pKa (amino)= 8.0; and pKa (R group) = 12.5). pH is 7
(b) The amino acid lysine has the following values of pK : PK1 =2.2, pK2 = 8.9, PKR = 10.5 (the pK, of the amino group in the side chain). At pH 7 it has the structure shown below (6). Draw the structure that you would expect for lysine at pH 9.7, indicating the charges as appropriate. HZN 0 HINA (2 marks) (c) Phenol (C6H5OH) and 2,4,6-trichlorophenol (C6H2C13OH) are both weak acids with pK, values of 9.89 and 6.21, respectively,...
Calculate the pI for this peptide. Gly Asp Lys Cys Glu His Met Table 1. Group pka c-teminus 3.5 his 6.0 n-terminus 9.0 lys 10.5 asp/glu 4.0 cys 8.4 tyr 10.5 arg 12.5
What about the pKa values of the R groups of the seven amino acids containing an ionizable R group? Tyr 10.5 Lys 10.5 Arg 12.5 Asp 3.9 Glu 4.1 His 6.0 Cys 8.4 Indicate the approximate net charge of each of these seven R groups at pH 7.4. Indicate the approximate net charge of each of these seven amino acids at pH 7.4. Note: remember the carboxyl and the alpha-amino group in addition to the ionizable (acidic or basic) R...