Question

Case Study: The parents took John, the 4 year old Greek patient to a pediatrician for...

Case Study:

The parents took John, the 4 year old Greek patient to a pediatrician for a checkup. A CBC revealed the following results:

CBCDIFFERENTIAL

WBC =11.4 x 109/LSegs=55%

RBC=1.7 x 1012/LBands=1%

Hgb=8.3 g/dLLymph=36%

Hct=24%Mono=7%

Plt=172 x 109/LEos=1%

MCV=69 fLModerate poikilocytosis, polychromasia, MCH=21 pgand many target cells; few teardrop cells observed

MCHC=29%

1. Based upon the indices, classify the anemia morphologically.

2. Name 3 disorders that frequently present with the same morphology that dominates this smear.

3. List 2 additional lab tests that would help confirm the diagnosis and predict the results of each.

Case Study:

The parents took John, the 4 year old Greek patient to a pediatrician for a checkup. A CBC revealed the following results:

CBCDIFFERENTIAL

WBC =11.4 x 109/LSegs=55%

RBC=1.7 x 1012/LBands=1%

Hgb=8.3 g/dLLymph=36%

Hct=24%Mono=7%

Plt=172 x 109/LEos=1%

MCV=69 fLModerate poikilocytosis, polychromasia, MCH=21 pgand many target cells; few teardrop cells observed

MCHC=29%

1. Based upon the indices, classify the anemia morphologically.

2. Name 3 disorders that frequently present with the same morphology that dominates this smear.

3. List 2 additional lab tests that would help confirm the diagnosis and predict the results of each.
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Answer #1

1. Megaloblastic anaemia

2. a) megaloblastic thalassemia

b) bone marrow infiltration

c) haemolytic anaemia

3. a) CBC test ( complete blood count test)

b) schilling test

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