1-Include a concise summary of the remaining starting material % for each substituent
2-Include the general rule that correlates EDG/EWG behavior of a substituent to its activating/deactivating effect
3-Include a concise summary of the major product(s) of each substituent
4- Include general rule that correlates EDG/EWG behavior of a substituent and the preferred regiochemistry of the reaction
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1-Include a concise summary of the remaining starting material % for each substituent 2-Include the general...
1- Include a concise summary of the remaining starting material % for each substituent 2- Include general rule that correlates EDG/EWG behavior of a substituent and the preferred regiochemistry of the reaction ОСН, ОСН, ОСН, OCHZ NO2 HNO3 H2SO4 + + NO2 anisole 0-nitroanisole (31%) m-nitroanisole (2%) NO2 p-nitroanisole (67%)
1 - Discuss correctly why each substituent favors the observed major product. (e.g. stability of the carbocation intermediate resonance hybrid, steric hindrance at reaction location) How does the stability of the intermediates (from the handout done during the lab) rationalize the observed products formed? Do more stable intermediate lead to more products or less 2- Create a general rule that correctly correlates EDG/EWG behavior of a substituent and the preferred regiochemistry of the reaction. Where do EDGs tend to substitute?...