Which substitution elimination pathway(s) is(are) favored by a high concentration of the attacking species (nucleophile base)?...
Which mechanism(s) listed below generally proceed(s) smoothly when a low concentration of neutral nucleophile base is used in the presence of a polar protic solvent? O a. Sy2 b. Syl and El c. El d. E2 e. Si f. Sn2 and E2
Which attacking species shown below would be the best choice to enforce an E2 pathway over an SN2 pathway for the reaction below? Attacking Species? BI CH; H -¢-o CH,MgB HC-0-0 CH; (a) H (b) (c) NH OH (d) SH (1) e Which solvent(s) listed below would be satisfactory in Sn2 reactions? HzC CH DMSO CH3CH,OH o HzC. Н.С DMF I II III a. I only b. II only c. III only d. I and II e. I and III...
Which attacking species shown below would be the best choice to enforce an E2 pathway over an Sp2 pathway for the reaction below? Attacking Species? Br H CH,MpBr HC-0 NH (a) H (b) e OH H₂C_&_• SH Els (d) (1)
H20 a = Proton transfer b=Lewis acid/base c = Radical chain substitution d-Radical chain addition e = Electrophilic addition f-El Elimination g=E2 Elimination h = Syl Nucleophilic substitution i-Sy2 Nucleophilic substitution Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a . i for your answers.
Which statement or set of conditions listed below is not consistent with an Syl reaction pathway? O a. Neutral nucleophile work just fine. b. The leaving group is typically the conjugate base of a strong acid. O c. The rate is not dependent upon the concentration of the nucleophile. d. The temperature is relatively "cooler" to reduce competing elimination products. e. The solvent is polar and aprotic. Of. The substrate has a leaving group that is typically on a 30,...
Which reaction pathway is favored given the following substrate and conditions? ci NaBr Acetone a. E2 b. Syl El c SX2 d. SN 2 E2 e. E1 f. Sni
strong nucleophile weak base strong bulky base strong nucleophile strong base Promote SN2/E2 weak nucleophile weak base Promote SN1/E1 Promote SN2 Promote E2 CH Br HS NCT HO CHO CHÚCHO NaNO NaOH NOME Noe HOORS Conjugate acids have pka 16-18 Conjugate acids Recall, you make hydroxide have pka 11 or alkoxide ons from the corresponding alcohol or water and Nat CH,OH (MOH) HO CH,CH,OH (EXOH) | HC-Ć-o to CH tert-BUOK NOCH KOHBU NEOBU The structures above are all ways of...
Which reaction pathway is favored given the following substrate and conditions? ci NaBr Acetone O a. Sn2 b. E2 OC. SNI d. SN2/E2 e. El f. Sni/E1 What is the major Organic product from the following sequence of reactions? O 1) NaNH2 2) Br ou O (b) 0 NHO i NH (d) (e (f) What is the systematic IUPAC name for the following Organic compound? o o a. Butanoic methanoic anhydride b. Ethanoic pentanoic anhydride c Octan-2,4-dione d. Pentylethanoate e....
pathway, substitution or elimination, will predominate and so a mixture of products is frequently observed. In contrast to the El reaction which involves a carbocation intermediate, the ElcB reaction takes place through a carbanion intermediate. Base-induced abstraction of a proton in a slow, rate-limiting step gives an anion which then expels the leaving group from the adjacent carbon. The reaction is particularly suited to the elimination of substrates which contain poor leaving groups two carbons removed from a carbonyl group....
OH 1. + HI .H2O Ci OCH3 2. CH,OH a Proton transfer b Lewis acid/base c Electrophilic addition d El Elimination e = E2 Elimination f SNI Nucleophilic substitution g Sy2 Nucleophilic substitution The rections above involve synthesis or reactions of alcohols and ethers. Identify the mechanism by which they proceed from among the mechanisms listed. Use the letters a -g for your answers. Submit Answer Retry Entire Group 9 more group attempts remaining