Draw a mechanism for the acetylation of p-methylaniline
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Draw a mechanism for the acetylation of p-methylaniline in reaction 3. Reaction 3: Acetylation NH2 NH2 + NH2 (acetic anhydride) NH2 NH2 m-methylaniline p-methylaniline O-methylaniline m-methylaniline HN o-methylaniline O p-methylacetanilide Procedure for Reaction 3: 1) The solution of the three isomers of methylaniline in ethyl acetate was cooled to 0 °C. 2) An equimolar amount of acetic anhydride to the quantity of p-methylaniline theoretically present in the solution was added dropwise with stirring. 3) The stirring was continued for 15...
That is the entire reaction and below is the question I need answered Reaction 3: Acetylation NH2 NH2 (acetic anhydride) NH2 NH2 0-methylaniline NH2 m-methylaniline p-methylaniline HN o-methylaniline m-methylaniline 0 p-methylacetanilide Procedure for Reaction 3: 1) The solution of the three isomers of methylaniline in ethyl acetate was cooled to 0°C. 2) An equimolar amount of acetic anhydride to the quantity of p-methylaniline theoretically present in the solution was added dropwise with stirring. 3) The stirring was continued for 15...
a) Which spot is likely the para isomer of methylaniline? How could you tell? b) Which spot is likely the acetylated para product (p-methylacetanilide)? How can you tell? c) Keeping in mind we are only trying to acetylate the para isomer of methylaniline, is the reaction complete? d) Draw a mechanism for the acetylation of p-methylaniline in reaction 3. Thank you The TLC shown below was taken in step 4 of the procedure for reaction 3: SM= 0,m,p-methylaniline Co= Co-Spot...
a) Which spot is likely the para isomer of methylaniline? How could you tell? b) Which spot is likely the acetylated para product (p-methylacetanilide)? How can you tell? c) Keeping in mind we are only trying to acetylate the para isomer of methylaniline, is the reaction complete? Thank you The TLC shown below was taken in step 4 of the procedure for reaction 3: SM= 0,m,p-methylaniline Co= Co-Spot RM= Reaction Mixture +-- SM CO RM Reaction 3: Acetylation NH2 NH2...
provide the reaction mechanism of 4-methylaniline reacting with water. include all resonance structures if applicable
13. In step 5 of reaction 3, the reaction mixture containing the products shown below in ethyl acetate is extracted twice with HCI. NH2 NH HN o-methylaniline m-methylaniline p-methylacetanilide a) Which products (shown above) from reaction 3 can react with HCl in an acid-base reaction? Show the mechanism for this acid-base reaction and give the structures that would result from the protonation of these products. Which phase (organic or aqueous) would these protonated products be soluble in? (6 points) Reaction...
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a) Which of the following reagents will reduce p-nitrotoluene to p-methylaniline? b) Which of the reagents in #8 will convert p-nitrotoluene to p-nitrobenzyl bromide? c) Which reagent in #8 will convert p-nitrotoluene to p-nitrobenzoic acid? A. W-K B. H2CrO4 C. H2, Ni D. NBS, light
a) Which products (shown above) from reaction 3 can react with HCl in an acid-base reaction? Show the mechanism for this acid-base reaction and give the structures that would result from the protonation of these products. Which phase (organic or aqueous) would these protonated products be soluble in? b) Which phase (organic or aqueous) would the p-methylacetanilide be found in? In step 5 of reaction 3, the reaction mixture containing the products shown below in ethyl acetate is extracted twice...