Question

Which of the following reactions (A-D) will not work as drawn: [1 pt] reaction A MeΝΗ, reactionc HO INAMO MeNH H2SO4 reaction B HO H2SO4 reaction D 5: Which compound below (A-E) is the product of the reaction in the box: [1 pt] product 1) propionyl chloride, AICI, 2) NaCN, HCI 3) LAH 4)H20 OH of more on one B: Which compound below will have the highest percentage of enol form in solution: [1 pt) & fu & l 7: Which answer lists the compounds below according to an increasing pk of the a-proton: .COBu D

Answer 1

neaction C neaction A MeNH2 host H2O Х WHne H₂O OH MeNHa X H₂ sou reaction D H₂S0y heaction B Reaction o Ester can'nt be hydrolysed by water it needs acid or base in @ atalytic amount Reaction B In presence of H₂ Song amide/esters get hy chrolyzed to acid. ① Propiony I chloride, Alla Na CN, nce LAH (4) H2O. CH3 NOCN, uce Mechanism ye, Hell OH Friedel Crafts Ho CN CH3 t NH2 LAH H₂O

Highest percentage of eno forma 8 fimu 0 Bu D B The compound that has most acidic Hydrgan will show the weighest percentage of enot form sehr -I effect of difluro methane, and - R of in group. А F -HO COBU -HT Bag stabilized by - R. effect of two groups H c THO group. P H D بی ام و - Омо ome •R of C- group istaltilise it THO "NO 4 NH group; and Nitrogen stabilise he charge. -R of The most acidic proton is present in B as it is stabilised by conjugation with two i groups B has highest enol content.

Strong acid house low pla value. pka. < order of o O NH Groen Bu L A حر to stabilize ane Ć has Donly groep it's charge, so it is least acidic