Question

a-carboxyl group pka Amino acid Ala a-amino group pka 9.7 2.3 Arg 9.0 9.0 Asnor Gin Asp or Glu Cys 9.8 10.8 His 9.2 9.2 9.1 C
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Answer #1

pI denotes the isoelectric point of amino acid. Amino acid form zwitter ion which is actually the pI.

So

pI is the average of the two pK.

pI = (pK1 + pK2) 1/2

=( 2.1 + 9.0) 1/2

= 11.2/2. = 5.6 ~5.5

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