Question

Part 1: Carboxylic Acids and their derivatives 1. Complete the following synthesis by addingthe appropriate reagent(s) (4 points Et Reagent(s) A Reagent(s)B 2 Oomplete the following synthesis by adding the appropriate reagent(s). (4 points Reagent(s) A Reagent(s) B 3. Complete the following synthesis by adingthe appropriate reagent(s). (4 points) он Reagent(s)A Reagent(s) B Page 1 of 13

Answer 1

1. The first step of the reaction is an esterification reaction.

So, reagent A id EtOH and conc. H₂SO₄

Second step of reaction is a nucleophiliic replacement of ester group by -NH₂ group.

So, reagent B is NH₃.

2. First step of the reaction is photochemical halogenation.

So, reagent A is Br₂/CCl₄ in presence of light.

Second step is conversion to an acid involving a grignard reaction

So, reagent B is i) Mg in dry ether followed by ii) CO₂ followed by iii) dilute acid.

3. First step of the reaction is a hydrolysis of cyanide to an acid.

So, reagent A is H₂O and HCl.

Second step is conversion of acid to acid chloride

So, reagent B is SOCl₂.