Question

4. Meta-analysis - Mean risk ratio Aa Aa To help reduce the risk of alcohol-related health problems in heavy drinkers, many health care institutions offer therapy sessions known as brief interventions. These are a small number (1-4) of short, motivational counseling sessions (usually under 30 minutes each), which include education and advice about the dangers of heavy drinking. A meta-analytical review conducted in 2002 of 56 clinical trials comparing outcomes of brief interventions with control conditions found positive evidence for brief intervention, increasing the likelihood of successful moderation or cessation of alcohol abuse among heavy drinkers. [Source: Moyer, A., Finney, J. w., swearingen, C. E., & Vergun, P (2002). Brief interventions for alcohol problems: A meta-analytic review of controlled investigations in treatment-seeking and non-treatment-seeking populations. Addiction, 97(3), 279-292.] Suppose you conduct a similar review of 5 clinical studies comparing the outcomes of brief interventions with those of control conditions. Results are shown in the following table, where the number of successes corresponds to the number of patients in each study that decreased or moderated their drinking during the trial period. Compute the risk ratios and log risk ratios for each study to complete the following table Success Total Success Total Risk Log Risk Ratio Study Treatment Treatment Control Control Ratio Study 1 56 Study 2 105 Study 3 34 Study 49 Study 5 158 118 633 69 59 317 40 1130 241 314 286 1026 28 104

Answer 1

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