Question

6. Natural products are a source for many efficacious drugs. Often these drugs can be found in the traditional folk medicines used by civilizations to time immemorial. This especially true in China where centuries of civilization have led to many folk remedies, cures or potions. While some are fallacious (e.g. rhino horns as an Viagra substitute), many have some scientific basis and one avenue of research is the search for these compounds, most of which have multiple chiral centers. The example below is a natural product recently discussed in the literature. Identify all chiral centers in this structure and list them as R or S. HQ H3CO OCH3

Answer 1