Question

I am in the process of making notecards for the purpose of studying for the MCAT and would like to just double check if my understanding is correct or if anything crucial should be added. (Note: This is soley a notecard answer, not an indepth explanation of the process. My goal is to simply answer this off recall and within 10-15 seconds.) Thank you for any help or comments.

Front of Card (question): High blood glucose levels can drastically affect blood vessels/blood pressure. Explain how, by using the concept of osmotic pressure and state what dictates that pressure, related to elevated blood glucose levels.

Back of Card (answer): Osmotic pressure is the force pushing against the blood vessel walls, preventing osmosis from occurring. That pressure is heavily dictated by the molar concentration or the van't Hoff factor (substrate dissociation). Glucose is nonvolatile and doesn't dissociate in the blood, therefore it only has a van't Hoff factor equal to one. The force directed against osmosis occurring is reduced, producing high blood vessel pressure from the addition of water from the interstitial fluid.

Answer 1

Basically the osmotic pressure depends on the solute concentration and temperature. High blood glucose increase the osmotic pressure.the decrease in blood volume makes the blood thicker.glucose is non volatile and it does not disassociate with blood hence forming osmotic pressure.which results into high blood vessels pressure.the increase in glucose levels leads to diabetes.

In the case of diabetes the solvent is water and solute is glucose.diabetic has High blood glucose so it is not absorbed by cells in body.which leads to high blood pressure.