I'm needing an explanation on how to do these two retrosynthesis problems.
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I'm needing an explanation on how to do these two retrosynthesis
problems.
Retrosynthesis. For each synthetic...
Please describe how each reaction will be accomplished. Alkyne and Nitrile Synthesis Retrosynthesis CH CH2 OH...
Please describe how each reaction will be accomplished.
Alkyne and Nitrile Synthesis Retrosynthesis CH CH2 OH ОН Br HCECH + Synthesis CH CH2 0,0 NMO HCOCH Li NH NaNH Benzyl bromide OH OH Retrosynthesis One-on-o EN Br Synthesis Br KCN er blan NH2 H3C 1) LAH 2) H30* NH CH3 Alkyne and Nitrile Synthesis Retrosynthesis CH CH2 OH OH Br H2=CH + Synthesis CH CH2 0.0 NMO Li NH, NaNH, Benzyl bromide HC SCH OH OH The starting material is...
Show by means of retrosynthesis, synthetic schemes and EXPLANATORY NOTES, how would you carry out the following synthesi...
Show by means of retrosynthesis,
synthetic schemes and EXPLANATORY
NOTES, how would you carry out the following
synthesis shown below. You are allowed to use any other
reagents and starting materials you choose as long as the chosen
substance(s) is/are used properly. Remember the
principles of selectivity and
control, and note any
regiochemical or stereochemical problems
that may possibly arise. Provide BRIEF
NOTES and COMMENTS for
EACH of the steps made, indicating any
special reaction conditions, catalysts
and solvents normally...
uiz Problems - Provide an answer for each in the space provided. 1. Suggest a reasonable...
uiz Problems - Provide an answer for each in the space provided. 1. Suggest a reasonable series of synthetic transformations (i.e. a series of reagents and reaction conditions) to prepare cis-2-methylcyclohexyl acetate CA) from trans-2-methylcyclohexanol (this problem is worth 4 points) H3C CH3 A (target molecule)
Write the structure of a major product when benzene reacts with neopentyl bromide (1-bromo-2, 2-dimethylpropane) in...
Write the structure of a major product when benzene reacts with neopentyl bromide (1-bromo-2, 2-dimethylpropane) in the presence of AlCl_3/heat Show the reaction mechanism of this reaction and name the product Using retrosynthetic analysis, devise a synthesis of 2-nitroterephthalic acid ft benzene by using any necessary organic and inorganic reagent (Assume that ortho and and para-isomers are easily separable in the laboratory.) Identify compounds A-C in the retrosynthesis shown below and suggest reagents for each synthetic stop.
please help 2. Syntheses Utilizing Substitution Reactions. For each whenie problew below, first write our a...
please help
2. Syntheses Utilizing Substitution Reactions. For each whenie problew below, first write our a retrosynthetic analysis. Then, write the forvand synthesis including all necessary reaction conditions and genes for each transformation. All of the syntheses below wille either Sulor S. Pay particularly close attention to whether your synthesis must be stereoselective Second BORS are required for forlate leuwing grow onlar 2 carbons) i inversion of configuration is necessary BOS 50% to 350 91 CHS
1) 2 (CH3),CHCH Br / Cul/ 4 Li? CHỊCH, CHỊCH 2) H30+ 2. Using any necessary reagents, show how the following synth...
1) 2 (CH3),CHCH Br / Cul/ 4 Li? CHỊCH, CHỊCH 2) H30+ 2. Using any necessary reagents, show how the following synthetic transformations may be achieved. Give reagents and conditions for each step. Include all synthetic intermediates compounds produced during the course of multi-step synthesis). NOTE: You may not use HOC OH 1. For each of the following questions, provide the missing reagents that can be purchased) and conditions or predict the MAJOR product. Indicate stereochemistry and identify a racemic...
1. Provide a complete retrosynthesis and forward synthesis of the target molecule below from the given...
1. Provide a complete retrosynthesis and forward synthesis of the target molecule below from the given starting materials. All carbons of the target must be from the given starting materials. You may use any reagents you find necessary. You may include more than one step over a reaction arrow, but please no more than 3 steps at a time. Please show the key intermediates in your synthesis for partial credit. (10 bonus points) For full credit, include a retrosynthetic analysis,...
show how to carry out the following synthetic transformations using any compounds with one or two...
show how to carry out the following synthetic transformations using any compounds with one or two carbon atoms, any necessary solvents, and any Inorganic reagents. Clearly indicate reaction conditions. More than one synthetic step will be required (work backwards!) 1-Bromopentane- 2-Chloropenia H-C=C-H H₃C Br H-C=C-H - Br CH3 CHO H-C=c-H HO HIC TOH meso H-C=C-H c=CH₂ H3C CH(CH2).CHCI - CH(CH2),CHCHCI Наснас н H3CH2CCECH 4 CH₂CH₃ H3CH2CCECCH2CH3 Br Br CH,CH,CHCHCH.CH meso trans Ph trans OH show in most stable chair conformation)...
how many synthetic connections for alkene and alkyne 2. Is the Zaitsev Rule wrong? Explain the following observation...
how many synthetic connections for alkene and
alkyne
2. Is the Zaitsev Rule wrong? Explain the following observation. Make comparative predictions about the rate constants ki and k2. 80% 20% on CH₂ 100% 3. Using curved arrows to show the movement of electron pairs, give a detailed mechanism for the following reactions. H2SO4 H20 195010 - + H20 H2SO4 H2O CH3 H3C-C-CH2-OH- CHE HECH = + H₂O H₃C CH₂ 4. See how many synthetic connections you can make on the...
2 problems including answer options [Review Topics) [References) In each case below select the synthetic procedure/s...
2 problems including answer options
[Review Topics) [References) In each case below select the synthetic procedure/s that could be used to carry out the transformation, giving the alcohol shown as the single major product. The procedures are: Hydroboration oxidation: alkene +BH3, then H,02, "OH. Oxymercuration: alkene + Hg(OAc)2, H2O, then NaBH4 OH a- CH3 CH3 Submit Answer Retry Entire Group 4 more group attempts remaining thetic procedure/s that could be used to carry out the transformation, + BHz; then H202,...
Please describe how each reaction will be accomplished.
Alkyne and Nitrile Synthesis Retrosynthesis CH CH2 OH ОН Br HCECH + Synthesis CH CH2 0,0 NMO HCOCH Li NH NaNH Benzyl bromide OH OH Retrosynthesis One-on-o EN Br Synthesis Br KCN er blan NH2 H3C 1) LAH 2) H30* NH CH3 Alkyne and Nitrile Synthesis Retrosynthesis CH CH2 OH OH Br H2=CH + Synthesis CH CH2 0.0 NMO Li NH, NaNH, Benzyl bromide HC SCH OH OH The starting material is...
Show by means of retrosynthesis,
synthetic schemes and EXPLANATORY
NOTES, how would you carry out the following
synthesis shown below. You are allowed to use any other
reagents and starting materials you choose as long as the chosen
substance(s) is/are used properly. Remember the
principles of selectivity and
control, and note any
regiochemical or stereochemical problems
that may possibly arise. Provide BRIEF
NOTES and COMMENTS for
EACH of the steps made, indicating any
special reaction conditions, catalysts
and solvents normally...
uiz Problems - Provide an answer for each in the space provided. 1. Suggest a reasonable series of synthetic transformations (i.e. a series of reagents and reaction conditions) to prepare cis-2-methylcyclohexyl acetate CA) from trans-2-methylcyclohexanol (this problem is worth 4 points) H3C CH3 A (target molecule)
Write the structure of a major product when benzene reacts with neopentyl bromide (1-bromo-2, 2-dimethylpropane) in the presence of AlCl_3/heat Show the reaction mechanism of this reaction and name the product Using retrosynthetic analysis, devise a synthesis of 2-nitroterephthalic acid ft benzene by using any necessary organic and inorganic reagent (Assume that ortho and and para-isomers are easily separable in the laboratory.) Identify compounds A-C in the retrosynthesis shown below and suggest reagents for each synthetic stop.
please help
2. Syntheses Utilizing Substitution Reactions. For each whenie problew below, first write our a retrosynthetic analysis. Then, write the forvand synthesis including all necessary reaction conditions and genes for each transformation. All of the syntheses below wille either Sulor S. Pay particularly close attention to whether your synthesis must be stereoselective Second BORS are required for forlate leuwing grow onlar 2 carbons) i inversion of configuration is necessary BOS 50% to 350 91 CHS
1) 2 (CH3),CHCH Br / Cul/ 4 Li? CHỊCH, CHỊCH 2) H30+ 2. Using any necessary reagents, show how the following synthetic transformations may be achieved. Give reagents and conditions for each step. Include all synthetic intermediates compounds produced during the course of multi-step synthesis). NOTE: You may not use HOC OH 1. For each of the following questions, provide the missing reagents that can be purchased) and conditions or predict the MAJOR product. Indicate stereochemistry and identify a racemic...
1. Provide a complete retrosynthesis and forward synthesis of the target molecule below from the given starting materials. All carbons of the target must be from the given starting materials. You may use any reagents you find necessary. You may include more than one step over a reaction arrow, but please no more than 3 steps at a time. Please show the key intermediates in your synthesis for partial credit. (10 bonus points) For full credit, include a retrosynthetic analysis,...
show how to carry out the following synthetic transformations using any compounds with one or two carbon atoms, any necessary solvents, and any Inorganic reagents. Clearly indicate reaction conditions. More than one synthetic step will be required (work backwards!) 1-Bromopentane- 2-Chloropenia H-C=C-H H₃C Br H-C=C-H - Br CH3 CHO H-C=c-H HO HIC TOH meso H-C=C-H c=CH₂ H3C CH(CH2).CHCI - CH(CH2),CHCHCI Наснас н H3CH2CCECH 4 CH₂CH₃ H3CH2CCECCH2CH3 Br Br CH,CH,CHCHCH.CH meso trans Ph trans OH show in most stable chair conformation)...
how many synthetic connections for alkene and
alkyne
2. Is the Zaitsev Rule wrong? Explain the following observation. Make comparative predictions about the rate constants ki and k2. 80% 20% on CH₂ 100% 3. Using curved arrows to show the movement of electron pairs, give a detailed mechanism for the following reactions. H2SO4 H20 195010 - + H20 H2SO4 H2O CH3 H3C-C-CH2-OH- CHE HECH = + H₂O H₃C CH₂ 4. See how many synthetic connections you can make on the...
2 problems including answer options
[Review Topics) [References) In each case below select the synthetic procedure/s that could be used to carry out the transformation, giving the alcohol shown as the single major product. The procedures are: Hydroboration oxidation: alkene +BH3, then H,02, "OH. Oxymercuration: alkene + Hg(OAc)2, H2O, then NaBH4 OH a- CH3 CH3 Submit Answer Retry Entire Group 4 more group attempts remaining thetic procedure/s that could be used to carry out the transformation, + BHz; then H202,...
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