Question

MATH 140 - Introduction to Statistics 1.36 2] Researchers examined a new treatment for advanced ovarian cancer in a mouse model. They created a nanoparticle-based delivery system for a suicide gene therapy to be delivered directly to the tumor cells. The grafted tumors were injected either with the new treatment or with only some buffer solution to serve as a comparison. The data below give the fold increase in tumor size after two weeks in 20 mice. A 1 represents no change; a 2 represents a doubling in volume of the tumor. 9.1 8.1 Buffer solution 7.8 70 6.8 5.4 5.4 4.1 3.8 3.3 Nanoparticle-delivered gene therapy 2.1 2.1 LS LS 14 12 11 11 4.1 3.5 Make a back-to-back stemplot to compare the two samples. That is, use one set of stems with two sets of leaves, one to the right and one to the left of the stems.(Draw a line on either side of the stems to separate stems and leaves.) Order both sets of leaves from smallest at the stem to largest away from the stem. What are the most important differences between the two groups? What can you conclude?

Answer 1

13 Back-to-back stem plot. leaves stem leaves Buffer Solution - Namo partide-delivered gene theraphy 8 3 3 5 # 5 816 o 7 8 (c) The most important differences are i for Nanoparticle-delivered gene theraphy most of the mice has their tamor size increased less than double of previous In Butter solution the increase of tumor is starts from 's' fold increase to 'a' fold increase ii) The range of nanoparticle - delivered gene theraphy, has more concentrated results with minimum tol to matinum holl. So the range is of only 3 folds (4-1) In Buffer Solution the increase of tumor minimum of 3.3 folds to maximum qui folds. so the range is of increase in 5.8 felds nearly double to the Nano particle theraphy. We can conclude that the Manoparticle- delivered gene theraphy is more effective in controlling the increase of tumor (grafted tumor) Compared to Buffer Solution.