a. Is ring opening of the epoxide in cortisol regiospecific? b. Is ring opening of the...
a. Is ring opening of the epoxide in cortisol regiospecific?
b. Is ring opening of the epoxide in arene oxides
stereospecific? What features of the
molecule led you to your choice? (Explain in 5 words or less.)
Homework Answers
Add Answer to:
a. Is ring opening of the epoxide in cortisol regiospecific?
b. Is ring opening of the...
Epoxide Ring-Opening Post Lab Question: There was a marked difference in the final product distribution from...
Epoxide Ring-Opening Post Lab Question: There was a marked difference in the final product distribution from this weeks acid-catalyzed reaction versus the base-catalyzed reaction. Was one set of reaction conditions more regiospecific than the other? If so, why do you think that this was the case? Explain your reasoning in detail.
Base-catalyzed ring opening of an epoxide with CH3O- as the nucleophile forms a molecule with: Base-catalyzed...
Base-catalyzed ring opening of an epoxide with CH3O- as the
nucleophile forms a molecule with:
Base-catalyzed ring opening of an epoxide with CH30-as the nucleophile forms a molecule with: o (epoxide) Two ether groups A conjugated diene Two hydroxyl groups An alkene and a hydroxyl group Hydroxyl group and an ether
Show the mechanism for the epoxide ring opening. a) b) 1) mCPBA 2) HBr 1) mCPBA...
Show the mechanism for the epoxide ring opening.
a)
b)
1) mCPBA 2) HBr 1) mCPBA 2) NaCN
Epoxide Ring Opening Post Lab Questions: 1 Reflux conditions are problematic when performing acid catalyzed epoxide...
Epoxide Ring Opening Post Lab Questions: 1 Reflux conditions are problematic when performing acid catalyzed epoxide ring opening reactions. Provide the potential side product(s) that would result from carrying out the following reaction under reflux conditions. You must be sure to show the side products of both the major and minors products of the reaction below: . 3PO4 Methanol Reflux
Which of the following amines can be prepared by ring opening of an epoxide with sodium...
Which of the following amines can be prepared by ring opening of an epoxide with sodium amide followed by reduction? OH NH2 OH NH2 OH HO -NH N 3 a. only 1 b. only 1 and 2 c. only 1 and 4 d. 1, 2, 3 and 4
9. Which of the following amines can be prepared by ring opening of an epoxide with...
9. Which of the following amines can be prepared by ring opening of an epoxide with sodium amide followed by reduction? CH OH Em Em a. only 1 b. only 1 and 2 c. only 1 and 4 d. 1, 2, 3 and 4 10. What is the IUPAC name of the following compound? OH HO. Y OH ÕH a. (2R 3R)-dihydroxybutanedioic acid b. (2S,3S)-dihydroxybutanedioic acid C. (2R,3S)-dihydroxybutanedioic acid d. (2S,3R)-dihydroxybutanedioic acid 11. Which of the following is the correct...
transformation could be achieved by a conrotatory ring closure followed by a dsrotatory ring opening could...
transformation could be achieved by a conrotatory ring closure followed by a dsrotatory ring opening could be done in the opposite order to achieve the same results. Draw both pathways, induding the The two step eaction conditions (thermal or light) and the intermediates, then explain which choice might be better. 12 Give the products for the following reactions. heat hv Ring closure is usually favored, so explain why, in this case, ring opening is favored. heat hv b) consider them...
(21) 3. Consider the Ring Opening Metathesis Polymerization method: the initiating system in ring opening metathesis...
(21) 3. Consider the Ring Opening Metathesis Polymerization method: the initiating system in ring opening metathesis polymerization reactions. ring opening metathesis polymerization reactions. (C) Formulate a detailed mechanism for the ring opening metathesis polymerization reaction. (d) What is the major polymer product formed in the reaction of cyclopentene with the WCI/AIEt catalyst system? (e) Formulate a detailed reaction pathway for the reaction of cyclopentene with MoCls/AlEts catalyst system and draw the structure of the polymer product. (1) What is the...
The acetylide ion attacks the epoxide, opening up the strained, three-membered ring and creating an alkoxide...
The acetylide ion attacks the epoxide, opening up the strained, three-membered ring and creating an alkoxide ion. After the reaction is complete, a proton source is used to protonate the alkoxide ion. In a synthesis, these two steps must be shown separately, because the acetylide ion will not survive in the presence of H30t. Using this information, complete the reaction diagram to propose a plausible synthesis for the following compound using acetylene as your only source of carbon atoms: Soep...
of 20-16. (a) In the cavity ring-down measurement at the opening this chapter, absorbance is given...
of 20-16. (a) In the cavity ring-down measurement at the opening this chapter, absorbance is given by ?(1 where L is the length of the triangular path in the cavity, c is the speed of light, ? is the ring-down lifetime with sample in the cavity. and To is the ring-down lifetime with no sample in the cavity. Ring- down lifetime is obtained by fitting the observed ring-down signal intensity I to an exponential decay of the form le", where...
Base-catalyzed ring opening of an epoxide with CH3O- as the
nucleophile forms a molecule with:
Base-catalyzed ring opening of an epoxide with CH30-as the nucleophile forms a molecule with: o (epoxide) Two ether groups A conjugated diene Two hydroxyl groups An alkene and a hydroxyl group Hydroxyl group and an ether
Show the mechanism for the epoxide ring opening.
a)
b)
1) mCPBA 2) HBr 1) mCPBA 2) NaCN
Epoxide Ring Opening Post Lab Questions: 1 Reflux conditions are problematic when performing acid catalyzed epoxide ring opening reactions. Provide the potential side product(s) that would result from carrying out the following reaction under reflux conditions. You must be sure to show the side products of both the major and minors products of the reaction below: . 3PO4 Methanol Reflux
Which of the following amines can be prepared by ring opening of an epoxide with sodium amide followed by reduction? OH NH2 OH NH2 OH HO -NH N 3 a. only 1 b. only 1 and 2 c. only 1 and 4 d. 1, 2, 3 and 4
9. Which of the following amines can be prepared by ring opening of an epoxide with sodium amide followed by reduction? CH OH Em Em a. only 1 b. only 1 and 2 c. only 1 and 4 d. 1, 2, 3 and 4 10. What is the IUPAC name of the following compound? OH HO. Y OH ÕH a. (2R 3R)-dihydroxybutanedioic acid b. (2S,3S)-dihydroxybutanedioic acid C. (2R,3S)-dihydroxybutanedioic acid d. (2S,3R)-dihydroxybutanedioic acid 11. Which of the following is the correct...
transformation could be achieved by a conrotatory ring closure followed by a dsrotatory ring opening could be done in the opposite order to achieve the same results. Draw both pathways, induding the The two step eaction conditions (thermal or light) and the intermediates, then explain which choice might be better. 12 Give the products for the following reactions. heat hv Ring closure is usually favored, so explain why, in this case, ring opening is favored. heat hv b) consider them...
(21) 3. Consider the Ring Opening Metathesis Polymerization method: the initiating system in ring opening metathesis polymerization reactions. ring opening metathesis polymerization reactions. (C) Formulate a detailed mechanism for the ring opening metathesis polymerization reaction. (d) What is the major polymer product formed in the reaction of cyclopentene with the WCI/AIEt catalyst system? (e) Formulate a detailed reaction pathway for the reaction of cyclopentene with MoCls/AlEts catalyst system and draw the structure of the polymer product. (1) What is the...
The acetylide ion attacks the epoxide, opening up the strained, three-membered ring and creating an alkoxide ion. After the reaction is complete, a proton source is used to protonate the alkoxide ion. In a synthesis, these two steps must be shown separately, because the acetylide ion will not survive in the presence of H30t. Using this information, complete the reaction diagram to propose a plausible synthesis for the following compound using acetylene as your only source of carbon atoms: Soep...
of 20-16. (a) In the cavity ring-down measurement at the opening this chapter, absorbance is given by ?(1 where L is the length of the triangular path in the cavity, c is the speed of light, ? is the ring-down lifetime with sample in the cavity. and To is the ring-down lifetime with no sample in the cavity. Ring- down lifetime is obtained by fitting the observed ring-down signal intensity I to an exponential decay of the form le", where...
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