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5. Sketch a typical neuronal action potential (AP), and describe the important events or conditions that drive or are otherwi
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euronacfon Poten tial peak 3 nP re laive of

Step 1 - Resting Potential

Sodium and potassium channels are closed. Na+ are more outside the cell; K+ are concentrated inside the cell. Potential difference: -70 mV.

Step 2 - Depolarization

Sodium channels open in response to a stimulus. Na+ rush into the cell according to the dictates of diffusion. Final potential difference +30 mV.

Step 3 - Repolarization

Na+ channels close and K+ channels open. K+ rush out of the cell according to the dictates of diffusion. Potential difference: slightly below -85 mV.

Step 4 - Resting Conditions Re-established

Na+ and K+ channels are closed. Sodium-potassium exchange pump moves Na+ out and K+ in. Resting potential difference: -70 mV.

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