Write the mechanism of the following substitution reaction Explain why Polar protic solvents favor SN1 reactions....
why Sn2 reactions will not work with polar protic solvents? draw structures to explain if possible please
4. Sn1 reactions are unimolecular and Sn2 reactions are bimolecular. What does this mean? Write the generic rate laws for Sn1 and Sn2 reactions. Which reagents do the rates of Sn1 and Sn2 reactions depend on? 5. Consider tert-butylchloride and 2-chloropropane. Which of these compounds is more likely to react via an Sn1 mechanism? Which is more likely to reactive via an Sn2 mechanism? Explain your answer. 6. Rank the following compounds in order of increasing likelihood of undergoing substitution...
Sodium borohydride reductions are typically run in polar protic solvents such as methanol or water. Vanillin is only sparingly soluble in water or methanol, thus for this reaction vanillin was dissolved in 1.0 M NaOH (aq). Explain with the use of a reaction mechanism why vanillin is more soluble in 1.0 M NaOH than water. [2.0 Marks]
Propose a mechanism for the following reaction under conditions that favor a SN1 reaction. HO -OH & Br
Compare and contrast SN1, SN2, E1 and E2 reactions. What are some obvious similarities and differences between each reaction pathway? What are the requirements for each reaction to work? Discuss why SN2 is in direct competition with E2 while SN1 is in direct competition with the E1 reaction pathway. What is the rate expression for each? Which reactions are concerted? Which reactions are step-wise? Which reactions are stereospecific and what is the stereospecificity of each that are? How do the...
6. Propose a mechanism for the following reaction under conditions that favor a SN1 reaction. Br HO Σ ΟΗ
Please Answer Both questions Propose a mechanism for the following reaction under conditions that favor a SN1 reaction. HO -ОН Br For the following reactions provide the mechanism and explain the relative relate of the reactions. KOC(CH3)3 rel rate = 1 Br trans KOC(CH3)3 rel rate > 500 Br cis
6. Propose a mechanism for the following reaction under conditions that favor a SN1 reaction. (16 points) HO X ОН Br
questions 7. Why are polar protic solvents preferred for Syl reactions? A. Solvent ionizability B. Hydrogen bonding C.Heat Capacity D.Both A and B E.Both B and C ene chloride)? 8. Why is triflate (A) a better leaving group then tosylate (B) OSICF В A A. Atomic Size B. Resonance C. Hybridization D.Polarizability E. Inductive Effects E 9. Which compound is the stronger Base? A. Lithium Hydroxide B. Sodium Acetate C. Triethyl amine D. Potassium tert-butoxide E. Water 10. What is...
For the chemical reaction answer the following questions: 1. Is the mechanism Sn1 or Sn2? 2. What kind of substrate reacts in the following reaction? (2 ° , 2 ° allylic , 3 ° ) 3. Is the role of the alkyl halide reactant an acid, base, electrophile, nucleophile , or both a nucleophile and base? 4. Is the role of the reagent KI an acid, base, electrophile, nucleophile , or both a nucleophile and base? 5. What is the...