Ans: Reagent 1: KI/H+ with Alcoholic KOH It acts on double bond followed dehydrohalogenation which close ring 2
Reagent 2: TsCl/H+: It replaces the hydrogen in -OH group and close the ring 4 by elimination of tosyl group
Indicate appropriate reagent and reactions conditions or a short reaction sequence that could be expected to...
For the following reaction sequence, supply the missing intermediate or reagent/solvent, as appropriate Extra Credit: For the following reaction sequence, supply the missing intermediate or reagent/solvent, as appropriate. 1) 2) H", H,O Br DMF Extra Credit: Over the arrow, write in the reagents needed to perform the following transformation. Be specific about the number of equivalents (moles) required for each reagent and about the order of the steps Br
Give the names of the reagent(s) and conditions (solvent, heat/no heat) that are expected to give the best yield in the synthetic transformation below. More than one reaction is needed. List the reagents and conditions separated by numbers for each separate reaction Give the names of the reagent(s) and conditions (solvent, heat/no heat) that are expected to give the best yield in the synthetic transformation below. More than one reaction is needed. List the reagents and conditions separated by numbers...
Give the names of the reagent(s) and conditions (solvent, heat/no heat) that are expected to give the best yield in the synthetic transformation below. More than one reaction is needed. List the reagents and conditions separated by numbers for each separate reaction.
5. What series of reagents and/or reaction conditions could be used to effect the following transformation in good overall yield? Number the steps in sequence 1, 2, 3, 4, etc.; enter 0 for a reaction that is not used. OH OH Br ? Br2, FeBr3 fuming H2SO4 HCl (conc), heat HC1, H2O, heat HBr
3. Draw the appropriate starting materials and indicate the appropriate reaction conditions needed that you would need in order to make the ester shown below. There is more than one correct answer. (5 pts) 4. Show reagents for the reactions below: (2 pts each, 6 pts total) OH CO,
Place the best reagent and conditions in the bins for each of the following reactions. (Stoichiometry is omitted.) Treating an acyl chloride with a Grignard reagent tends to form (via two steps) an alcohol. A different reagent is needed to stop the reaction at the ketone product.
13. Which of the following reagent(s) could not be used to carry out the following transformation? A) Zn(Hg), HCI 14. Predict the product for the following reaction sequence. NaBH, CH,OH
Each of the following could be accomplished using a reagent listed below. Indicate a reagent for cach transformation. Use a given reagent only once. Normal aqueous workup is implied. putza o the سلام ce OCHg & och al OCH3 1125 B oats routs outs -Out Reagents: (a) Na H (b) Na BH (C) Li Al H (d) Li Al(-+) (e) (CH, Culi (0) CHIMgBr (g) CHILi (h) (CH, Zn OCH Na G) NaOCHCH3OH (k) NaOH/H20
1. Give a sequence of reactions to accomplish the following transformation? Show mechanism 2. What reagent(s) would accomplish the following? Show mechanism. R-CH2-NH2 R-C-NH2 3. What would result from the reactions shown below? Hsco-s-OCH3 large excess) NaOH нон H,0 но ОН "ОН (a and B) 4. Predict the major product of the following reaction. CHNNH 3 equivalents) но CHCH2OH Heat он CH2OH Draw the Haworth projection for chair conformation of a-D-Glucopyranose (shown below) CH2OH HO H OH OH
Reactions In each reaction box, place the best reagent and conditions from the list below. 2) Br2 HBr (CH3)3C0- 03 in CH2Cl2 NaBH4 in EtOH CH3COO- BHY/THE H2Oz/NaOH CH3CH20-