Question

What is the LAST reaction called? and how are the reagents used in this reaction (H2/Pd-C)? Thank you.

Adrenergic (Sympathomimetic) Dr What is the LAST reaction called? and how are the reagents used in this reaction (H2/Pd-C)?

Answer 1

Answer:

1)last reaction called debenzylation

2) starting material disoved in methanol or ethanol [preffered ethanol,because methanol (flash point 12⁰C may catch fire] and degassed with nitrogen to remove oxygen(for safe from fire).Then Pd/C was added supply the hydrogen gas in autoclave or hydrogen bladder.

after compelted the reaction, pd/c filter through celite ( make sure that should not get drry),filterate concentrated to get product.the above celite part quinched in 2NHCl)