Question

4) Cisplatin (PCh(NHala) was the first inorganic chemotherapeutic. It has the ability to interact with DNA in tumor cells, leading to cell death. Transplatin, the isomer of csplatin, does not have the same effects in cells. The differences in biological activity are a result of the different geometries of the molecules. Note: Both of these molecules are planar.) Cisplatin has Czy symmetry, whose multiplication table we examined in dass. Determine the point group of transplatin, assuming the hydrogens on the ammines do nat destroy the symmetry elements present. The symmetry elements and operations (3 total are given, along with some additional information. Complete the multiplication table below. Axes have been provided for you on the elements, please use them. Cely Coly ? (xy) o(yz) ColE) ? (yz) ?(xy)

Answer 1