11. Which of the following reactions take place more rapidly when the concentration of the nucleophile...
(20) 7. Which reaction of the following pairs will take place more rapidly? a) CH, CH, CH, Br + CH, OH - CH, CH, CH, Br + CH20- b) CH, Br + CH, OH - CH, Br + CH, SH - c) (CH3)2CHCHCI (CH3)2 CHCH,I + Ng + Nz - - CH, Br + (CH3)3N CH, Br + (CH3)3P - (Polar Protic Solvents) e) CH, I + OH- - CHỞI + CH4, CD,
By what factor does the rate increase when the concentration of the nucleophile is increased by 4 times and the electrophile is increased by 5 times for the following reaction. Br CN ~ CN + Br®
6. Which Sw2 reaction of each pair would you expect to take place more rapidly? Show products and explain your answer. 1-bromobutane + methanol or 1-bromobutane + sodium methoxide
CHEM 330 Homework # 9 Name: Due: 11/06/19 Identify which of the following two reactions you would expect to occur more rapidly and then explain your choice. (2 pts) 4. НЕг HЕг 5. Suggest an efficient target synthesis for the following transformation. (3 pts) OH 2 steps Br Provide the complete mechanism for the following reaction. (6 pts) 6 но HаРОд Н-о
Complete the following reactions. Be sure to evaluate each reaction in terms of substrate, nucleophile, leaving group, and solvent in order to best judge the nature of the reaction and the products formed. Complete the following reactions. Be sure to evaluate each reaction in terms of substrate, nucleophile, leaving group and solvent in order to best judge the nature of the reaction and the product(s) formed. (5 pts) CH2O СН,ОН H₃C & CH₂ H₂O. Ethanol CH3 CH,Br OH CHCN Which...
Which reaction will take place readily (more easily)? KBr (a) OH + Н,о Br HBr (b) "ОН + Br A. Reaction (a) B. Reaction (b) C. Both D. Neither 7. Which of the following reactions will proceed the fastest by an SN2 reaction? (a) (b) NaBr NaBr NaBr Which of the following reactions will proceed the fastest by an SN1 reaction? 8. (b) NaBr NaBr (c) NaBr
Which SN2 reaction of each pair would you expect to take place more rapidly in polar protic solvent Aapidhy Au a n ote selmat ? a) n-PrCl aoo»?r-o- +a° vs R-Pr-O-Et Hd! -rCIEtoH Pr-o-Et t cP b) A-Prcit oo. vS. d)n- Br 4.0 M) * Heo' APia-e N-r C4-0M) eo(20M) oH
By what factor does the rate increase when the concentration of the nucleophile is increased by 3 times and the electrophile is increased by 2 times for the following reaction or CN CN + Bre
With explanation please -- thanks! 2. (8 pts) Which of the following substitution reactions will readily take place as written? Indicate by circling YES or NO. . OET EtOH NaBr YES or NO YES or NO DMF NaSH BjTso Br HS Br YES or NO NaBr Br DMSO YES or NO DMF TSO = tosylate 20
Which of the choices explains why one nucleophile is stronger than another nucleophile? More than one answer is possible. It is also possible that NONE of these is correct. 7 A stronger nucleophile is larger than another nucleophile. A stronger nucleophile has a less electronegative nucleophilic atom than another nucleophile. A stronger nucleophile has less steric hindrance than another nucleophile. Using this information, in methanol, CH3OH, which of the following is a stronger nucleophile, trimethylamine, (CH3)3N, or dimethylether, (CH3)20? SS...