Question

2. An article published recently in the journal Organic & Biomolecular Chemistry describes the first organic synthesis of two marine natural products. Seven steps of the synthesis are sho below. Fill in reagents that would accomplish the following transformations. wn OTBDMS OTBDMS OH OTBDMS OTBDMS OH OH OTBDMS OH OTBDMS OH

0 0
Add a comment Improve this question Transcribed image text
Answer #1

Sockution TBDMS 2) μ OTBDMS りNaNn2 00MS Linellar Mi hlovkup 아 매

Add a comment
Know the answer?
Add Answer to:
2. An article published recently in the journal Organic & Biomolecular Chemistry describes the first organic...
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for? Ask your own homework help question. Our experts will answer your question WITHIN MINUTES for Free.
Similar Homework Help Questions
  • this is an organic chemistry synthesis question, and I am having a little bit of trouble...

    this is an organic chemistry synthesis question, and I am having a little bit of trouble getting started. Any help with the mechanism would be appreciated! thanks! 2. The following reactions are from an article published by Masamune and Sharpless in Science, describing stereoselective synthesis of hexose sugars. a) The following conversion requires two reaction steps, the second one being protection of a diol as a cyclic acetal. Draw a reasonable mechanism for the first step of this reaction (NaOH,...

  • Topic: Organic Chemistry Please make all drawings very clear. Please show all work and side products...

    Topic: Organic Chemistry Please make all drawings very clear. Please show all work and side products along with brief explanations. Thank you. Each of the following transformations can be carried out in no more than three steps. Fill in the reagents required 3. for each step. If a step is not needed, mark an X for that step. а. 1 2. 3. b. 1 NEt2 2. 3. C. 1 он OPh Н. н 2. 3. d. OH 2. 3. е....

  • 2.Help, this got me really confused. ORGANIC CHEMISTRY 353 UPPER LEVEL. THANKS 6. (21 pts.) Fill...

    2.Help, this got me really confused. ORGANIC CHEMISTRY 353 UPPER LEVEL. THANKS 6. (21 pts.) Fill in the missing reagents and conditions or products to complete the synthesis below: 1. DA, THE GO! N H 3.H30, heat Br MeO-B OME

  • Hi, Would someone mind helping me with the following organic chemistry question. Please justify/explain your answer....

    Hi, Would someone mind helping me with the following organic chemistry question. Please justify/explain your answer. Thank you! ________________ QUESTION 21. Fill in the missing product, reagent, or substrate for each of the following transformations. Use wedge/dash notation, as appropriate, to show stereochemistry. 1. 03 2. S(Mei2 - Li 一 COSH Me-CI | Q- AICI: CO2H Two products include stereochemistry): Bry, CCI OH Br + enantiomer

  • organic chemistry 1.1 pt) Which reagent would you use to effect the following transformation of a...

    organic chemistry 1.1 pt) Which reagent would you use to effect the following transformation of a diol into a keto acid? ОН Reagent? CH,CHCH,CH,CH,OH - CH,CCH,CH,сон a) Jones(H2Cr2O7) b) Tollens c) mCPBA d) Collins(PCC) e) LiAlH4 2.(2 pts) Circle the TWO compounds that yield a stable Grignard reagent when treated with magnesium in ether. Br CHÚC HỌC=CH- CH,OH HN 3.(2 pts each) Reactions. Complete each reaction shown here. HỌC=CH- + HC=CH- -CH OH он 1. CH CH MgBrCH,CH,CH=CHCCH2CH3 2.H2O Сн,...

  • could someone please help me out in organic chemistry? Last Name- - First Same 1. Write...

    could someone please help me out in organic chemistry? Last Name- - First Same 1. Write the products of the following reactions. If there is no reaction write NR (30 points). a) CHCH.CH-Br + 2Li => "X" +LiBr: X=? C) 2 "X" + Cul Lil + "Y": Y- S and water d) (U) Y + 2. Starting from CH CH Br and diisopropyl amine, describe how you would prepare lithium diisopropy! amide (LDA), LINR, where R=Isopropyl (5 points) 2. Starting...

  • Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry....

    Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. My two target molecules are number 2 and number 12 in the last page. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the...

  • 6. An article in the ASCE Journal of Energy Engineering (1999, Vol. 125, pp 59-75) describes...

    6. An article in the ASCE Journal of Energy Engineering (1999, Vol. 125, pp 59-75) describes a study of the thermal inertia properties of autoclaved aerated concrete used as a building material. Seven samples of the material were tested in a structure, and the average interior temperatures ('C) reported were as follows Do all parts below a. [S) Compute the sample mean and the sample s 23.01, 22.22, 22.64, 23.62, 24.59, 23.15, 21.83. tandard deviation (just answer, no justification needed)...

  • please help me with Organic Chemistry/Alkenes problems. Thank you! Directions: Place your answers to the following...

    please help me with Organic Chemistry/Alkenes problems. Thank you! Directions: Place your answers to the following questions in the spaces provided. 1. A common problem in the acid-catalyzed hydration of alkenes is the formation of an ether byproduct. Show the formation of the ether byproduct in relation to the reaction below by providing a curved-arrow mechanism for its formation. (2 pts) H30+ Н,0 OH Ans. 2. Which is the correct sequence of steps necessary to complete the following reaction? он...

  • Page 1 Synthesis using Carbonyl O-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules...

    Page 1 Synthesis using Carbonyl O-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the organic starting material (what you have to work backwards toward) depends...

ADVERTISEMENT
Free Homework Help App
Download From Google Play
Scan Your Homework
to Get Instant Free Answers
Need Online Homework Help?
Ask a Question
Get Answers For Free
Most questions answered within 3 hours.
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT