Question

Cyclooctyne is the smallest cycloalkyne which is stable at normal temperatures. Show the sequence of reactions needed to complete the synthesis of the deuterium-labeled cyclooctanol shown in the image below. Assume that any necessary reagents can be obtained in isotopic forms.

DH mill。

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Answer #1

D2D BD Lindlars catalyst NaSH Pnduut oidatin i done to et desicd oduut

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