Need help with these shelf-life calculations!! Step by step would be great! Thanks
1. The specific decomposition rate k of an experimental drug obtained from Arrhenius plot is 3.4 x 10-4 hr-1 at room temperature. If the time required for 10% of a drug to degrade (t90%) represents a reasonable limit of degradation for the active ingredient and is designated as shelf-life, what will be the shelf-life in hours of this drug:
2. The shelf life of an API in a solution was found to be 25 days. What is the drug
1. The specific decomposition rate k of an experimental drug obtained from Arrhenius plot is 3.4 x 10-4 hr-1 at room temperature. If the time required for 10% of a drug to degrade (t90%) represents a reasonable limit of degradation for the active ingredient and is designated as shelf-life, what will be the shelf-life in hours of this drug:
Arrhenius plot
k = 3.4 x 10-4 hr-1
Reaction is of first order from the unit of k.
10% degradation, 90%A remains.
A/A0 = 0.9
Ln(A0/A) = k*t90
Shelf-life time t90 = Ln(1/0.9)/(3.4*10^-4) = 310hr
2. The shelf life of an API in a solution was found to be 25 days. What is the drug
Need help with these shelf-life calculations!! Step by step would be great! Thanks 1. The specific...