Question

A graduate student was attempting synthesize meta-nitrobenzoic acid from benzene. a. If he/she started the synthesis with a nitration of benzene first, what product will be formed? b. Show the necessary reaction scheme in proper order to synthesize the desired product. c. Using carbon NMR, what specific peak can you look for to determine which product was produced

Answer 1

ChemNMR 13C Estimation Pratorol of the C-13 MR Prediction: (tit=S) Answer Hi student, This simple question but confusinug. 1 will explain in details Node Shi Base Ine Comment ppm rel. to TAS) HO с 147,8 128.5 1-banzena 19.9 -0.1 -0.5 163.6 a. product fonned by nitration of beuzene is nitrobenzeue 131.1 eneral corrections 131.1 1-benzene NO, 133. 1239 IINO.-IISO 2.1 -0.4 1-C(-01-o eneral corrections 17 3 CH 129.1 129.5 1-benzene OT Nitration 1205 128.1 general e02 Leclǐuus CE 123.9 128.5 1-benzene 4.3 1.6 b synthesis of meta-nitrobenzoic acid: in this synthesis first form acid from benzene. Other step is nitaration of acid to form mctanitrobcuzoic acid becausc -COOH is mctadircction group eneral correct.ions CH 133.7 123.5 1 -E(-01-0 COOH COOH СНУ eneral corrections 10-0 eneral corrections 1-2:C"C"C"C"C"C"! CH 129.5 128.5 1-banzone friedel crafts alkylation -C.1 KMn04 HNO2-H,SO4 с 163.6 1E6.0 1-carboxyl Nitration 8,4 eneral corrections NO2 60 20 PPM