12 28. (10 points) starting from bromobutane. Design a synthesis of the compound below using m...
10. Select the compound that can not be made using the malonic ester synthesis: O O OH MeO Оме OH Ph OH A. B. Ph C. D. 11. In general both the malonic ester and acetoacetate synthesis require the addition of dilute acid in order to generate the final product. Why? A. the alkoxy cation needs to be eliminated C. the ionized cation partitions to the aqueous layer B. the stabilized enolate adds a proton in the separatory funnel D....
Please design a synthesis route that leads to the following compound starting from malonic ester. You can use any reagents.
10. Select the compound that can not be made using the malonic ester synthesis: O o O OH MeO OMe OH Ph ОН A. B. Ph C. D. 11. In general both the malonic ester and acetoacetate synthesis require the addition of dilute acid in order to generate the final product. Why? A. the alkoxy cation needs to be eliminated C. the ionized cation partitions to the aqueous layer B. the stabilized enolate adds a proton in the separatory funnel...
6. Design a synthesis of the following compound starting from benzene and any other organics and inorganics (12 pts) OH 6. Design a synthesis of the following compound starting from benzene and any other organics and inorganics (12 pts) OH
synthesis of 1-bromobutane Using the included 'H NMR spectra, identify which compound is the starting material and which is the product by drawing the Lewis structures directly on the corresponding spectrum. Then designate which peaks correspond to which protons on your Lewis structure (designate using (a), (b), etc.). -3.592 -3.578 -3.567 2.356 2.349 0.50 1.535 - 1.518 1500 -1480 1464 - 1.381 1.362 100 343 0.99 -1.325 -1.306 -1.289 -0.903 0.00 4.884- -0.867 1511 0.00 1.0 'H NMR NH -он...
Synthesis 10. Give a reasonable synthesis for the following compound from the indicated starting material. You may use any other organic or inorganic reagents you wish unless otherwise indicated. The desired product for each reaction you propose must be the one of the predominant products. Give the reactants, conditions (where appropriate) and products of each synthetic step. NO MECHANISMS! [6 points) Make med og som en ons starting with SO3H
For the compounds named below, (1) draw the structure of each compound (2) using benzene or toluene as the only aromatic starting material devise a synthesis of each compound. b. p-nitroethylbenzenec. p-bromonitrobenzene d. p-isopropylbenzenesulfonic acid
1. Write the structural formula of each of the following co (1) m-chlorobenzoyl chloride; (b) p-ethylbenzamide: (©) (e) 2-ethyl-1-butanamine; (f) dibenzylamine; (g) a B-lacta the following compounds: (28 pts) Pethylben (s) acetoacetic ester; (d) diethyl malonate: of each of the following reactions: (30 pts) 2. Identify the principal organic product of each of the (a) acetic anhydride and 2-pentanol (b) 4-methyl-3-penten-2-one and ammonia in water solut er solution (c) acetophenone (methyl phenyi ketone) and benzalder (d) methyl butanoate and LDA...
Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. My two target molecules are number 2 and number 12 in the last page. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the...
Propose a simple synthesis for the compound shown below, using the provided starting material and any organic or inorganic Reagent. Draw all intermediates. (Use alkene and alkyne reactions)