Question

4 a and b please

4. (10 Points) Give a reasonable explanation for each of the following observations: a. The rate constant for the base catalyzed hydrolysis of compound below is almost 100 times smaller than that for compound li. towapsow oooo 4. continued b. The rate constant for base catalyzed hydrolysis of compound il below is 40 times greater than that for compound Iv. mited States) DSC0ODA MacBook Pro

Answer 1

Y ea -O-CH2CH3 -- och stenie interaction I Base catalized hy dnolylls of anesten R-800 R H POH. - RETOR ooh M Olt : e -00+ HOCHZ See in the above, beleven the estens I & I, the Carbon contre adjacent to the Canbonyl centre is more crowoled than the ester I. Hence when the formen is attacked by Oolt, it epeatte faces some stenic Repuision beteveen the.Cotz group and -014 group.ro the hycholysis becomes Slowen for the case I waed on the other thene no such type stensie interaction presar because it atoms are for too mall to create hich type of tensic repulsion. fy Hochz dom Bow To H2o El och Altho Loo Hocha 2 Hone In the case of the strony electrons with drawing group is present which can stabilise the cool anich mone by its treason withdrawing natine., makes the eshe hydrolysis very facile. - whereas in the and case it fr only benzene mery is preseep which also stabilised by the nafananeo Stinetine on mone comoectly safonance

goes ' tompound B exteriores hydroly's mone farsten than the compould . ^ Ralonance: woo ooo oo a tot LI → ET