BOTH THE QUESTIONS INVOLVES THE CONCEPT THAT Beta- keto acids READILY DECARBOXYLATE ON HEATING AND LIBERATES CARBON DI OXIDE GAS.
Problem 18.23 Provide a structural formula for the major product from each of the following reactions....
8. [18 pts) Provide the expected organic product(s) from each of the reactions below. Ignore the stereochemistry. No mechanism required! (3 points for each organic product, switching the major and minor will be penalized) a. Major: NaOCH; E2 Br b. Major Minor OH E2 Br 3 products in total CH,OH ΕΙ 6. 19 pts] For each of the following reactions, give the organic product(s), and include the stereochemistry when applicable. No mechanism required! (3 points for each organic product) a....
Provide the major organic product (including stereochemistry if appropriate) for each of the following reactions: 3. 1) NaH а) (CH)-СHCH,ОН 2) (CH),СНОСH-CH,Br b) excess HI 1) Hg(OAc),/H,O 2) NaBHĄ/HO¯ 1) NaOH 2) PҺOH d) CH,CH,Br 1) BH3/THF 2) H-0,/Но" НCIZnClz он g) MCPBA h) 1) mCPBA 2) CH3O¯ 1) mCPBA 2) CH,ОН/Н"
4. Give the major organic product(s) for each of the following reactions or sequences of reactions. H Br 1. N.CN 2. NaOH,H,O, heat 3.H30 Ind o do CH,COOH 1. LiAlH, THF, heat 2.H,0 HO CH Br 1. NaCN, acetone 2.H30, heat h ome couco C:03, H30* он
Give the major organic product from each of the following reactions (including any appropriate stereochemistry): 1. (10) Give the major organic product from each of the following reactions (including any appropriate stereochemistry): HBr H20 2 ) O 3 2) H 2O2 1) BH 3 2) NaOHH H20 2 CH ,OFH 3 heat CH3 Br NaOCH 3
7. Give the structural formula for the organic product from each of the following reactions. (12 marks) o CHACHACH + K2CrO + H2SO4 a. O OH HCCHCH2 + 2 Cu2+ HO CH, b. NH CH3CHCH3 + 2 Agt HO C=0 H c . CH OH + 2 Cu2+ HO d. 11 NH3 CHCH CH CH + 4 Agt H2O κτιριοι, e. O f. CHỊCH CHỊCH + K2CrO + H2SO4 -
(10 pts) Predict the major product for each of the following reactions. 2. Ho Br 1. NaOH/Br 2. H,O NaOH/H20 1. NaOCH,CH 2. H,0 1. NaOCH,CH, 2 HO (10 pts) Predict the major product for each of the following reactions. 2. Ho Br 1. NaOH/Br 2. H,O NaOH/H20 1. NaOCH,CH 2. H,0 1. NaOCH,CH, 2 HO
Provide the major organic product from each of the following reactions. NH2 (1) cat. HA (2) NaBH3CN 2 Br (1NaCN Edit (2) LiAIH (3) H o 2 Br (1)NaNs Edit (2) LiAIH (3) H O 2 Edit (1) NH3, HA (2) NaBH3CN NH2 2 Edit (2) LiAIH (3) H3o
ovide the expected major product(s) of each of the following reactions. Br (CH) COK CHCO,H NaOCH, CH,OH CACOK, axcomdet B 40, NaOH, 40, ? W Brą, H, 0 NaOH, H,O o H2 Lindlar catalyst 1. HC = CNa 2. H,0 ܂ ܙܗܘܘ ܂ ܘܦ ܢܫ ܂ CH,ONa CH,OH H0 H,SO H, SO 1. RCO,H 2. LiAIH, HBN) -
6. Draw the condensed structural formula for the ester formed in each of the following reactions: C-OH H+, heat + CH3 -CH2-OH CH3 0 H*, heat CH3-CH-0-OH + CH2-OH = b
For each of the following reactions, draw the structure of the major organic product in the box provided. Each numbered set of reagents above or below the arrow represents a complete separate reaction. For multi-step reactions, give only the structure of the final product. КОН (alc) Br b) KOtBu HOtBu Br THE H2SO4 OTS КОН (ale) CH,CH Show Specific Stereochemistry CH(CH3)2 HCI H- CH CH_CH KOH (ale) Show Specific Stereochemistry NaOCH HOCH KO:Bu HOBu