Question

Please show work and answer.

6. The Km of RBC GLUT1 for glucose is 18 mg/dL while the Km for liver GLUT2 is 360 mg/dL. At a blood glucose concentration of 60 mg/dL, GLUT1 and GLUT2 are working at what percentage of their Vmax? A. GLUT1 at 75% Vmax and GLUT 2 at 75% Vmax B. GLUT1 at 14%Vmax and GLUT at 14%Vmax C. GLUT 1 at 116%Vmax and GLUT2 at 75%Vmax D. GLUTI at 75%Vmax and GLUT2 at 14%Vmax E None of the above

my professor gave this hint to us to solve the problem.

He also said that I could find the relationship between S and Km and substitute that into the Michaelis-Menten equation.

Answer 1

None of the above option is correct i.e. option (e) is correct answer.The explaination is given in the following figure.

Accarding to michelas- Menton (mm) equation; velocity of Iv=Vman [S] reaction Km+ [S] where [s] = Substrate concentration Far AUT1 ; Km² 18mg/dL, [S] = 60 mg/dL V= man X 18 18+60 = 23% Kman 3Vman Far AUT2; Km= 360mg/dL, [s] = Gong/dL V = Vman X Go 360+ 60 H = 14%. Kmani Thus, Answer is ALUTI at 23% Vman and GLUTZ at 14%. V mana nie. None of the above answer is carents CS Scanned e Nonae of CamScanner