Question

Can you answer these please?

Aldol Assignment Write the answers to 1,3 & 5 on a sheet of paper and be prepared to email it to me. 1. Why is it important to maintain equivalent proportions of reagents in this experiment? 2. What side products do you expect in this experiment? How are they removed? 3. The geometric possibilities for products are cis/cis, trans/trans or trans/cis. Which isomer do you think is the major product and why?. 4. What evidence do you have that the product is a single geometric isomer? (melting point?) Explain. 5. Please write a complete mechanism for this reaction. A Double Aldol Condensation The Synthesis Of Dibenzalacetone NaOH H +

Answer 1

1) It is important to maintain an equivalent amount of reagents in the reaction because excess reactants would cause hydrolysis of the product back to the reactant if the reaction is reversible in nature. Secondly, if we don't have an equivalent amount of reagents we can't attain our desired product with good yields and high purity. Impure products will form more in case of less amount of reagents.

3) As it is mater of stability out of three possibilities trans/trans > cis/trans > cis/cis. In cis/cis it suffers more strain and unfavorable steric interaction of substituents will come into account. However, trans isomers are more stable than cis which have high thermochemical stability.

نهان Naoh هر | OH