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IVUL. c7) (4 points) A biochemist in a pharmaceutical company is trying to design an inhibitor...
i need help answering questions EXTRA CREDIT 1. A pharmaceutical company has developed a new chemotherapy...
i need help answering questions
EXTRA CREDIT 1. A pharmaceutical company has developed a new chemotherapy drug (STOP2D) which functions as an inhibitor of the enzyme Split2. This enzyme is part of a pathway that promotes cell division. Suppose that in clinical trials, some of the patients become resistant to the drug. In order to determine the mechanism of resistance, the proteome of the patients is examined and it is found that the expression of Split2 is normal; however, the...
You are a scientist at a pharmaceutical company and want to develop a new drug that...
You are a scientist at a pharmaceutical company and want to develop a new drug that can decrease heart rate. In order to do this you decided to target the beta 2 adrenergic receptor. You want to design a peptide that gets incorporated into the plasma membrane and interferes with beta 2 adrenergic receptor signaling. 1) Design the peptide sequence (10) and describe briefly each of the features and function of the sequences you incorporated (20). 5 sentences for each)...
Question 18 4 points Save Answer A famous car company is trying to test whether there...
Question 18 4 points Save Answer A famous car company is trying to test whether there is a difference in the average popularity customer rating for new car models A and B. What test should this company use to provide for the manufactory based on the above information? ANOVA Two samples test o O One sample test ttest of a population proportion
Dukeville Company Interior Design Dukeville is an interior-design firm owned and managed by Jason Duke, a...
Dukeville Company Interior Design Dukeville is an interior-design firm owned and managed by Jason Duke, a reputed interior designer Mr. Duke charges his clients $400/hr for his consultation services and serves clients for 50 hours a week on average. A typical engagement is between 20 and 40 hours. Mr. Duke uses Garza & Co., a local firm, to bill his clients and track receivables balances. He pays a monthly fee of $3,000 to Garza & Co. Mr. Duke is satisfied...
1. A researcher suspects that consumption of some fruit berries found in the amazon basin may...
1. A researcher suspects that consumption of some fruit berries found in the amazon basin may have positive or negative effects on hemoglobin function. Can you predict what the effect of eating a significant amount of the berries would be on adult hemoglobin binding and distribution of oxygen if one of the phytochemicals in the berries has been found to be a competitive inhibitor of 2,3-Bisphosphoglycerate (2,3 BPG) (3 points). What do you think would be the effect of the...
Any help would be appreciated! N-tosyl L-AA-chloromethylketones (see structure to the right) have proven to be...
Any help would be appreciated!
N-tosyl L-AA-chloromethylketones (see structure to the right) have proven to be effective irreversible inhibitors of members of the family of serine proteases. Given what you have learned about the substrate specificity pocket in this class of enzymes, which of the compounds listed below would you expect to be the most effective inhibitor for elastase? CIRCLE the most correct answer. R = Met side chain R = Leu side chain R = Ala side chain R...
QUESTION 4 8 points Save Answer Company A uses LIFO and Company B uses FIFO. Assume rising prices. In analyzing li...
QUESTION 4 8 points Save Answer Company A uses LIFO and Company B uses FIFO. Assume rising prices. In analyzing liquidity and profitability of the two firms, which of the following statements is true? Company B will have higher owners' equity. Company A will have lower cost of goods sold Company A will have higher liabilities. Company B will have lower income tax payments. It is impossible to say anything about the two firms since they use different inventory methods....
4. The CRISPR-Cas9 system is an important new technique in molecular biology. What is the natural...
4. The CRISPR-Cas9 system is an important new technique in
molecular biology. What is the natural function of this system?
Describe how you would use this system to generate a null mutation
in another organism (i.e. explain Figure 6-43). How does it work?
What is the modification of the method that allows for correction
of a mutation (e.g. the mouse crystalline gene)? And lastly, what
are the problems with the CRISPR system?
FIGURE 6-43 Single-nucleotide mutations
can be introduced into...
1. Alaa works for a pharmaceutical company that has developed a new drug. The patent on...
1. Alaa works for a pharmaceutical company that has developed a new drug. The patent on the drug will last 17 years. She expects that the drug’s profits will be $2 million in its first year and that this amount will grow at a rate of 5% per year for the next 17 years. Once the patent expires, other pharmaceutical companies will be able to produce the same drug and competition will likely drive profits to zero. What is the...
Case: Geekdom Games Bob Phillips, the owner of Geekdom Games contacted your consulting company last week...
Case: Geekdom Games Bob Phillips, the owner of Geekdom Games contacted your consulting company last week to discuss the expansion of his business and the role of information systems in that expansion. Geekdom Games is a small game design business located in St. Louis, Missouri. Geekdom has been in business for five years and has three full-time employees in addition to Mr. Phillips. Geekdom Games produces interactive, fantasy based board games and role playing games similar to Dungeons and Dragons....
i need help answering questions
EXTRA CREDIT 1. A pharmaceutical company has developed a new chemotherapy drug (STOP2D) which functions as an inhibitor of the enzyme Split2. This enzyme is part of a pathway that promotes cell division. Suppose that in clinical trials, some of the patients become resistant to the drug. In order to determine the mechanism of resistance, the proteome of the patients is examined and it is found that the expression of Split2 is normal; however, the...
Question 18 4 points Save Answer A famous car company is trying to test whether there is a difference in the average popularity customer rating for new car models A and B. What test should this company use to provide for the manufactory based on the above information? ANOVA Two samples test o O One sample test ttest of a population proportion
Dukeville Company Interior Design Dukeville is an interior-design firm owned and managed by Jason Duke, a reputed interior designer Mr. Duke charges his clients $400/hr for his consultation services and serves clients for 50 hours a week on average. A typical engagement is between 20 and 40 hours. Mr. Duke uses Garza & Co., a local firm, to bill his clients and track receivables balances. He pays a monthly fee of $3,000 to Garza & Co. Mr. Duke is satisfied...
Any help would be appreciated!
N-tosyl L-AA-chloromethylketones (see structure to the right) have proven to be effective irreversible inhibitors of members of the family of serine proteases. Given what you have learned about the substrate specificity pocket in this class of enzymes, which of the compounds listed below would you expect to be the most effective inhibitor for elastase? CIRCLE the most correct answer. R = Met side chain R = Leu side chain R = Ala side chain R...
QUESTION 4 8 points Save Answer Company A uses LIFO and Company B uses FIFO. Assume rising prices. In analyzing liquidity and profitability of the two firms, which of the following statements is true? Company B will have higher owners' equity. Company A will have lower cost of goods sold Company A will have higher liabilities. Company B will have lower income tax payments. It is impossible to say anything about the two firms since they use different inventory methods....
4. The CRISPR-Cas9 system is an important new technique in
molecular biology. What is the natural function of this system?
Describe how you would use this system to generate a null mutation
in another organism (i.e. explain Figure 6-43). How does it work?
What is the modification of the method that allows for correction
of a mutation (e.g. the mouse crystalline gene)? And lastly, what
are the problems with the CRISPR system?
FIGURE 6-43 Single-nucleotide mutations
can be introduced into...
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